CD130/gp130 抗体
Quick Overview for CD130/gp130 抗体 (ABIN1383684)
抗原
See all CD130/gp130 (IL6ST) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognises the Gp130, common subunit for IL-6, IL-11, OSM, LIF, CNTF, CT-1 receptors, a 130-140 kDa protein
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纯化方法
- Ion exchange chromatography
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过滤
- 0.22 μm filtered
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免疫原
- Natural soluble gp130,Myeloma X63/AG.8653 x Balb/c spleen cells
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亚型
- IgG2b, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
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储存液
- Without preservative
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储存条件
- 4 °C
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储存方法
- Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
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: "Studies on the interleukin-6-type cytokine signal transducer gp130 reveal a novel mechanism of receptor activation by monoclonal antibodies." in: The Journal of biological chemistry, Vol. 275, Issue 7, pp. 4579-86, (2000) (PubMed).
: "Ciliary neurotrophic factor is a regulator of muscular strength in aging." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 19, Issue 4, pp. 1257-62, (1999) (PubMed).
: "Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein." in: The Journal of biological chemistry, Vol. 271, Issue 25, pp. 14764-72, (1996) (PubMed).
: "Purification and characterization of the soluble interleukin-6 receptor from human plasma and identification of an isoform generated through alternative splicing." in: European journal of biochemistry / FEBS, Vol. 236, Issue 3, pp. 837-42, (1996) (PubMed).
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: "Studies on the interleukin-6-type cytokine signal transducer gp130 reveal a novel mechanism of receptor activation by monoclonal antibodies." in: The Journal of biological chemistry, Vol. 275, Issue 7, pp. 4579-86, (2000) (PubMed).
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- CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
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别名
- CD130
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背景
- Gp130
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分子量
- 130-140 kDa
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途径
- JAK/STAT Signaling, Cellular Glucan Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Cancer Immune Checkpoints
抗原
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