CD40 抗体 (PE)
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- 抗原 See all CD40 抗体
- CD40
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This CD40 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- Mouse CD40
- 免疫原
- mouse CD40-human IgG1 fusion protein
- 亚型
- IgG2a
- Top Product
- Discover our top product CD40 Primary Antibody
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- 限制
- 仅限研究用
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- 浓度
- 0.1 mg/ml
- 储存条件
- 4 °C
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- 抗原
- CD40
- 别名
- CD40 (CD40 产品)
- 别名
- Bp50 antibody, CDW40 antibody, TNFRSF5 antibody, p50 antibody, AI326936 antibody, GP39 antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TRAP antibody, Tnfrsf5 antibody, TNFSF5 antibody, CD40 molecule antibody, CD40 antigen antibody, CD40 antibody, Cd40 antibody
- 背景
- Anti-mouse monoclonal antibody (clone 3/23) reacts with CD40 which is ex- pressed on B lymphocytes and on a subset of both CD4 and CD8 T cells in the adult (but not neonatal) spleen . The level of CD40 on B cells is enhanced following activation by LPS . The interactions of CD40 with its ligand CD40L are responsible for generating humoral responses, germinal center formation, and generating B cell memory . Stimulat- ing cells with immobilized 3/23 mAb increases expression of CD86 (B7.2) on B cells 1,3 Though the 3/23 mAb itself is a weak mitogen, it produces a synergistic proliferative B cell response with IL-4 or with mitogenic antibodies against surface Ig 1,3 . Costimulation with 3/23 mAb and IL-4 rescues B cells from apoptosis induced by hypercross-linking of sIgM or sIgD The 3/23 clone is suitable for use in flow cytometry and acetone fixed frozen tissue sec- tions
- 途径
- NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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