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CD40 抗体

CD40 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal unconjugated
产品编号 ABIN133941
发货至: 中国
  • 抗原 See all CD40 抗体
    CD40
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    小鼠
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    大鼠
    克隆类型
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    单克隆
    标记
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    This CD40 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS)
    特异性
    Mouse CD40
    纯化方法
    Purified
    亚型
    IgG2a
    Top Product
    Discover our top product CD40 Primary Antibody
  • 应用备注
    This antibody is suitable for use in flow cytometry.
    限制
    仅限研究用
  • 浓度
    0.2 mg/ml
    储存条件
    4 °C
  • 抗原
    CD40
    别名
    CD40 (CD40 产品)
    别名
    Bp50 antibody, CDW40 antibody, TNFRSF5 antibody, p50 antibody, AI326936 antibody, GP39 antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TRAP antibody, Tnfrsf5 antibody, TNFSF5 antibody, CD40 molecule antibody, CD40 antigen antibody, CD40 antibody, Cd40 antibody
    背景
    Anti-mouse monoclonal antibody reacts with CD40 which is expressed on B lymphocytes and on a subset of both CD4 and CD8 T cells in the adult (but not neonatal) spleen . The level of CD40 on B cells is enhanced following activation by LPS . The interactions of CD40 with its ligand CD40L are responsible for generating humoral responses, germinal centre formation, and generating B cell memory . Stimulating cells with immobilized 3/23 mAb increases expression of CD86(B7.2) on B cells 1,3 . Though the 3/23 mAb itself is a weak mitogen, it produces a synergistic proliferative B cell response with IL-4 or with mitogenic antibodies against surface Ig 1,3 . Costimulation with 3/23 mAb and IL-4 rescues B cells from apoptosis induced by hypercross-linking of sIgM or sIgD . Other applications of the 3/23 mAb include IHC of acetone-fixed frozen sections This antibody is suitable for use in flow cytometry.
    途径
    NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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