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Integrin beta 2 抗体 (Biotin)

ITGB2 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal WT-3 Biotin
产品编号 ABIN133277
发货至: 中国
  • 抗原 See all Integrin beta 2 (ITGB2) 抗体
    Integrin beta 2 (ITGB2)
    适用
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    大鼠
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This Integrin beta 2 antibody is conjugated to Biotin
    应用范围
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    Flow Cytometry (FACS)
    特异性
    Rat CD18 (LFA-1 chain).
    克隆位点
    WT-3
    亚型
    IgG1
    Top Product
    Discover our top product ITGB2 Primary Antibody
  • 限制
    仅限研究用
  • 浓度
    0.1 mg/ml
    储存条件
    4 °C
  • 抗原
    Integrin beta 2 (ITGB2)
    别名
    CD18 (LFA-1 Chain) (ITGB2 产品)
    别名
    CD18 antibody, LAD antibody, LCAMB antibody, LFA-1 antibody, MAC-1 antibody, MF17 antibody, MFI7 antibody, 2E6 antibody, AI528527 antibody, Cd18 antibody, Lfa1 antibody, ITGB2 antibody, itgb2 antibody, itgb2-a antibody, itgb2-b antibody, integrin subunit beta 2 antibody, integrin beta 2 antibody, integrin subunit beta 2 S homeolog antibody, ITGB2 antibody, Itgb2 antibody, itgb2.S antibody
    背景
    LFA-1 (lymphocyte function associated molecule-1) is one of the leukocyte integrins. It is a heterodimer consisting of and subunits of 160-170 kDa and 95-100 kDa respectively. LFA-1 promotes non-antigen dependent adhesion of T-cells to a variety of lymphoid cells that bear its complementary receptor I-CAM-1 (1). It has a broad distribution and is found on most common lymphocytes. ABIN133277is specific for the subunit of LFA-1. This antibody also recognizes MAC-1 and p150, 95 as well as LFA-1, since they all contain the same subunit. It inhibits homeotypic aggregation of PHA blasts and blocks the binding of rat lymphocytes to purified rat ICAM-1 (1). Applications include immunoprecipitation, flow cytometric analysis and immunohistochemistry, cryostat sections, and in vivo/in vitro functional studies (1,2,3).
    途径
    NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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