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FAK 抗体

PTK2 适用: 人, 小鼠, 大鼠 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN127083
发货至: 中国
  • 抗原 See all FAK (PTK2) 抗体
    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 330
    • 17
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    克隆类型
    • 324
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    多克隆
    标记
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    This FAK antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    特异性
    The antibody recognizes 125 kDa FAK.
    纯化方法
    Protein A Chromatography.
    免疫原
    Recombinant full length human FAK.
    Top Product
    Discover our top product PTK2 Primary Antibody
  • 应用备注
    Western Blot: 1-2 μg/mL. Immunoprecipitation: 5-20 μg/mL. Immunocytochemistry: 10-20 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 50 % Glycerol, 1 % BSA, and 0.02 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原
    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
    别名
    FAK1 / PTK2 (PTK2 产品)
    别名
    FADK antibody, FAK antibody, FAK1 antibody, FRNK antibody, PPP1R71 antibody, p125FAK antibody, pp125FAK antibody, PTK2 antibody, Fadk antibody, mKIAA4203 antibody, fak antibody, fak1a antibody, ptk2 antibody, ptk2a antibody, wu:fa18c04 antibody, zgc:66114 antibody, CG10023 antibody, CT28129 antibody, DFAK antibody, DFak antibody, DFak56 antibody, Dfak antibody, Dfak56 antibody, DmFAK antibody, Dmel\\CG10023 antibody, Fak56 antibody, Fak56D antibody, fak56 antibody, protein tyrosine kinase 2 antibody, protein tyrosine kinase 2 L homeolog antibody, PTK2 protein tyrosine kinase 2 antibody, protein tyrosine kinase 2ab antibody, Focal adhesion kinase antibody, PTK2 antibody, ptk2.L antibody, Ptk2 antibody, ptk2ab antibody, Fak antibody
    背景
    Focal adhesion kinase was identified as a 125 kDa substrate for the intrinsic protein tyrosine kinase activity of Src encoded pp60. The deduced amino acid sequence of FAK p125 has shown it to be a cytoplasmic protein tyrosine kinase whose sequence and structural organization are unique as compared to other proteins described to date. Localization of p125 by immunofluorescence suggests that it is primarily found in cellular focal adhesions leading to its designation as focal adhesion kinase (FAK). FAK is concentrated at the basal edge of only those basal keratinocytes that are actively migrating and rapidly proliferating in repairing burn wounds and is activated and localized to the focal adhesions of spreading keratinocytes in culture. Thus, it has been postulated that FAK may have an important in vivo role in the reepithelialization of human wounds. FAK protein tyrosine kinase activity has also been shown to increase in cells stimulated to grow by use of mitogenic neuropeptides or neurotransmitters acting through G protein coupled receptors.Synonyms: FADK1, FAK, Focal adhesion kinase 1, Protein-tyrosine kinase 2, pp125FAK
    基因ID
    5747
    NCBI登录号
    NP_722560
    UniProt
    Q05397
    途径
    Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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