MAP2K3 抗体
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北京 101111
Quick Overview for MAP2K3 抗体 (ABIN127077)
抗原
See all MAP2K3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects MKK3
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纯化方法
- Protein A affinity purified
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免疫原
- E. coli-expressed full-length human MKK3
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应用备注
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Western Blot: 0.5-4 μg/mL. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C/-80 °C
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储存方法
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
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别名
- MAP2K3
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背景
- MKK3 is a protein kinase that phosphorylates the p38 MAPK. Phosphorylation by MKK3 occurs on threonine and tyrosine residues and increases the activity of p38 to stimulate transcription factors ATF2 and Elk-1. MKK3, together with MKK6, serves as upstream regulators of p38 MAPK activation. A structural variant, MKK3b, has been identified that contains 29 more amino acids at its N-terminus.Synonyms: Dual specificity mitogen-activated protein kinase kinase 3, MAP kinase kinase 3, MAPKK 3, MEK3, MKK3
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基因ID
- 5606
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NCBI登录号
- NP_002747
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UniProt
- P46734
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途径
- MAPK Pathway, TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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