PPP3CA 抗体
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- 抗原 See all PPP3CA 抗体
- PPP3CA (Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA))
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适用
- 人, 小鼠, 大鼠, Cow, 兔, Hamster
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PPP3CA antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 特异性
- The immunoaffinity purified antibody detects a 61 kDa band, corresponding to the expected molecular weight of Calcineurin A on immunoblots. The antibody specificity is confirmed by specific peptide inhibition in immunoblotting studies.
- 纯化方法
- Affinity purified
- 免疫原
- Synthetic peptide corresponding to residues surrounding amino acids 267 of human Calcineurin A.
- Top Product
- Discover our top product PPP3CA Primary Antibody
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anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) (AA 1-84) antibody
PPP3CA 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 2G8 unconjugated
anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) (Middle Region) antibodyPPP3CA 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 马, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) (AA 21-51) antibodyPPP3CA 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) antibodyPPP3CA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) antibodyPPP3CA 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal CALNA-2353 unconjugated
anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) (N-Term) antibodyPPP3CA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) (N-Term) antibodyPPP3CA 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 马, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) antibodyPPP3CA 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) (AA 432-481) antibodyPPP3CA 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 马, Pig, 小鸡, 非洲爪蟾, 猴, 豚鼠, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) (N-Term) antibodyPPP3CA 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 马, Pig, 小鸡, 非洲爪蟾, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot: 1-4 μg/mL. Immunoprecipitation: 10-20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.2 mg/mL
- 缓冲液
- PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C/-80 °C
- 储存方法
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- 抗原
- PPP3CA (Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA))
- Abstract
- PPP3CA 产品
- 别名
- CALN antibody, CALNA antibody, CALNA1 antibody, CCN1 antibody, CNA1 antibody, PPP2B antibody, 2900074D19Rik antibody, AI841391 antibody, AW413465 antibody, CN antibody, Caln antibody, Calna antibody, CnA antibody, Calna1 antibody, calcineurin antibody, caln antibody, calna antibody, calna1 antibody, ccn1 antibody, cna1 antibody, ppp2b antibody, fj46e08 antibody, si:dkeyp-79c2.2 antibody, wu:fj46e08 antibody, ppp3ca antibody, protein phosphatase 3 catalytic subunit alpha antibody, protein phosphatase 3, catalytic subunit, alpha isoform antibody, protein phosphatase 3, catalytic subunit, alpha isozyme antibody, protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) antibody, protein phosphatase 3, catalytic subunit, alpha isozyme L homeolog antibody, serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform antibody, PPP3CA antibody, Ppp3ca antibody, ppp3ca antibody, ppp3ca.L antibody, LOC100205420 antibody
- 背景
- Calcineurin is a calcium/calmodulin-dependent serine/threonine protein phosphatase. The active enzyme is a heterodimer consisting of a catalytic A subunit of 61 kDa and a myristylated regulatory B subunit of 19 kDa that binds calcium. The catalytic A subunit consists of an amino terminal catalytic domain, followed by calmodulin and B subunit binding sites, and a caboxyl-terminal autoinhibitory domain. Calnineurin is the target of immunosuppressant drugs such as cyclosporin A and FK506. Calcineurin controls the translocation of nuclear factors of activated T cells (NFAT), a family of transcriptional activators that control the expression of cytokine genes essential to immune response, from the cytosol into the nucleus of activated T cells. Calcineurin has been proposed to play an important role in mediating calcium-activated cell death.Synonyms: CALNA, CAM-PRP catalytic subunit, CNA, Calmodulin-dependent calcineurin A subunit alpha isoform, PP2B catalytic subunit, Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, protein phosphatase 2B catalytic subunit alpha
- 基因ID
- 5530
- NCBI登录号
- NP_000935
- UniProt
- Q08209
- 途径
- RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Synaptic Membrane, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling
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