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CD25 抗体 (PE)

IL2RA 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal OX-39 PE
产品编号 ABIN120430
发货至: 中国
  • 抗原 See all CD25 (IL2RA) 抗体
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    适用
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    大鼠
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD25 antibody is conjugated to PE
    应用范围
    • 202
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    Flow Cytometry (FACS)
    特异性
    Recognizes the alpha chain of rat CD25, otherwise know as IL-2 receptor alpha, a 55 kDa type I membrane glycoprotein, expressed by activated T cells but not resting lymphocytes. CD25 is also expressed by dendritic cells found in the thymus medulla. This clone has been described reacting with paraffin-embedded material following PLP fixation (periodate-lysine-paraformaldehyde). Clone OX-39 has been shown to weakly inhibit the binding of IL-2 to Con-A stimulated spleen blasts (1).
    纯化方法
    Protein G purified immunoglobulin fraction
    免疫原
    Con A stimulated Rat T cells.
    克隆位点
    OX-39
    亚型
    IgG1
    Top Product
    Discover our top product IL2RA Primary Antibody
  • 应用备注
    Flow Cytometry: use 10 μL of neat antibody to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Reconstitute with 1 mL distilled water.
    缓冲液
    PBS pH 7.4 with 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
    有效期
    6 months
  • 抗原
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    别名
    CD25 / IL2RA (IL2RA 产品)
    别名
    CD25 antibody, IDDM10 antibody, IL2R antibody, TCGFR antibody, IL2RAC antibody, IL-2RA antibody, Il2r antibody, Ly-43 antibody, interleukin 2 receptor subunit alpha antibody, interleukin-2 receptor subunit alpha-like antibody, interleukin 2 receptor, alpha chain antibody, IL2RA antibody, Il2ra antibody, LOC100222957 antibody
    背景
    The Interleukin 2 Receptor alpha and beta chains, together with the common gamma chain, constitute the high affinity IL2 receptor present on activated T and B cells, thymocyte subset, pre B cells and T regulatory cells. Homodimeric alpha chains result in low affinity receptor, while homodimeric beta chains produce a medium affinity receptor. Normally an integral membrane protein, soluble IL2 Receptor alpha has been isolated and determined to result from extracellular proteolysis. Alternately spliced IL2 Receptor alpha mRNAs have been isolated, but the significance of each is presently unknown.Synonyms: IL-2 receptor alpha subunit, IL-2-RA, IL2-RA, Interleukin-2 receptor alpha chain, TAC antigen, p55
    基因ID
    25704
    NCBI登录号
    NP_037295
    UniProt
    P26897
    途径
    JAK/STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
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