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CD25 抗体

IL2RA 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7074349
发货至: 中国
  • 抗原 See all CD25 (IL2RA) 抗体
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    适用
    • 171
    • 106
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    小鼠, 大鼠
    宿主
    • 129
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    克隆类型
    • 209
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    多克隆
    标记
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    This CD25 antibody is un-conjugated
    应用范围
    • 202
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    大鼠
    纯化方法
    Affinity purification
    免疫原
    KLH conjugated Synthetic peptide corresponding to Mouse IL2RA
    Top Product
    Discover our top product IL2RA Primary Antibody
  • 应用备注
    WB (M,R) 1: 500-1: 1000, IHC/IF (M,R) 1:200-1:1000/1:250-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    别名
    IL-2 Receptor alpha (IL2RA 产品)
    别名
    CD25 antibody, IDDM10 antibody, IL2R antibody, TCGFR antibody, IL2RAC antibody, IL-2RA antibody, Il2r antibody, Ly-43 antibody, interleukin 2 receptor subunit alpha antibody, interleukin-2 receptor subunit alpha-like antibody, interleukin 2 receptor, alpha chain antibody, IL2RA antibody, Il2ra antibody, LOC100222957 antibody
    背景
    IL-2Rα(Activated T cells IL-2Rα Chain 55), also kown as membrane interleukin-2 receptor (mIL-2R) or CD25, is a protein encoded by IL2RA gene in Human. This protein is 55 kDa which is the high affinity composition of IL-2R. Few IL-2α chains will express in inactive T cells, while the expression will remarkably increase followed by IL-2 accumulation, when T cell surface receptor (TCR) is active. IL-2αchains will become soluble interleukin-2 receptor (sIL-2R) when they are detached from cell membrane into serum, and the molecular weight of sIL-2R is 45 kDa. The concentration of sIL-2R in serum can be used for a mark to measure T cells activation and IL-2Rα chains expression.
    分子量
    45 kDa
    基因ID
    16184
    NCBI登录号
    NP_032393
    UniProt
    P01590
    途径
    JAK/STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
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