CD130/gp130 抗体
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Quick Overview for CD130/gp130 抗体 (ABIN120026)
抗原
See all CD130/gp130 (IL6ST) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody specifically recognises soluble and membrane bound gp130 receptor. This antibody has been reported to block the activity of IL-6.
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纯化方法
- Ion exchange chromatography
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免疫原
- Natural soluble gp130 receptor. Spleen cells from immunised BALB/c (Iffa Credo) mice were fused with cells of the X63.Ag8.653 mouse myeloma cell line.
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亚型
- IgG1
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anti-Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 392-566) antibody
IL6ST 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 238-500) antibodyIL6ST 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 73-231) antibodyIL6ST 适用: 人, 猴 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 8D4D2 unconjugated
anti-Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 26-323) antibodyIL6ST 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 871-899), (C-Term) antibodyIL6ST 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB17993 unconjugated
anti-Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (pSer782) antibodyIL6ST 适用: 人, 大鼠 WB, ELISA, ICC, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 651-750) antibodyIL6ST 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 678-857) antibodyKO Validated IL6ST 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 678-857) antibodyIL6ST 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) antibodyIL6ST 适用: 人 WB, IHC, ELISA, FACS, IP, Func 宿主: 小鼠 Monoclonal B-P4 unconjugated
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应用备注
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ELISA. Flow Cytometry: 0.2 μg/106cells, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
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别名
- CD130 / IL6ST
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背景
- CD130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.Synonyms: IL-6R-beta, IL6 receptor beta, Interleukin-6 receptor subunit beta
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基因ID
- 3572
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NCBI登录号
- NP_002175
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UniProt
- P40189
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途径
- JAK/STAT Signaling, Cellular Glucan Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Cancer Immune Checkpoints
抗原
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