TNFRSF1A 抗体
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- 抗原 See all TNFRSF1A 抗体
- TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
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适用
- 人, 兔
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TNFRSF1A antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Enzyme Immunoassay (EIA), Radioimmunoassay (RIA)
- 纯化方法
- Affinity chromatography on Protein A
- 免疫原
- Purified human tumor Necrosis Factor Receptor type 1. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NSO myeloma cell line.
- 克隆位点
- H398
- 亚型
- IgG2a
- Top Product
- Discover our top product TNFRSF1A Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 248-428) antibody
TNFRSF1A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 22-211) antibodyTNFRSF1A 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibodyTNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (HRP)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal HRP
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (FITC)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal FITC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (Alkaline Phosphatase (AP))TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal Alkaline Phosphatase (AP)
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (Biotin)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal Biotin
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (PE)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal PE
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (APC)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal APC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (PerCP)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal PerCP
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- 应用备注
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Flow Cytometry. ELISA. Radioimmunoassay. Removal of sodium azide is recommended prior to use in functional assays. Clone H398 may be used to detect high levels of TNFR1, in western blotting under reducing conditions, such as recombinant material, but it is not suitable for detection of TNFR1 in normal cells in this application.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS, pH 7.4 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
- 别名
- CD120a / TNFR1 (TNFRSF1A 产品)
- 别名
- CD120a antibody, FPF antibody, MS5 antibody, TBP1 antibody, TNF-R antibody, TNF-R-I antibody, TNF-R55 antibody, TNFAR antibody, TNFR1 antibody, TNFR1-d2 antibody, TNFR55 antibody, TNFR60 antibody, p55 antibody, p55-R antibody, p60 antibody, TNF-R1 antibody, TNF-alphaR1 antibody, TNFRI antibody, TNFRp55 antibody, TNFalpha-R1 antibody, Tnfr-2 antibody, Tnfr1 antibody, fpf antibody, tbp1 antibody, p55-r antibody, tnf-r antibody, tnfar antibody, tnfr1 antibody, cd120a antibody, tnfr55 antibody, tnfr60 antibody, xtnfr1 antibody, wu:fj65b10 antibody, zgc:85914 antibody, TNFR I antibody, TNFRSF1A antibody, TNFA antibody, cTNF antibody, TNF receptor superfamily member 1A antibody, tumor necrosis factor receptor superfamily, member 1a antibody, TNF receptor superfamily member 1A S homeolog antibody, tumor necrosis factor antibody, TNFRSF1A antibody, Tnfrsf1a antibody, tnfrsf1a.S antibody, tnfrsf1a antibody, TNF antibody
- 背景
- Tumor Necrosis Factor (TNF) is a cytokine whose function is mediated through two distinct cell surface receptors (TNF Receptor I and TNF Receptor II) that are included in the TNF Receptor superfamily along with FAS antigen and CD40. TNF Receptors I and II are 55 and 75 kDa members, respectively, of a family of cell surface molecules including nerve growth factor receptor, Fas/Apo1, CD30, OX40, and 41BB, which are characterized by cysteine rich motifs in the extracellular domain. While TNF Receptor I and TNF Receptor II share 28 % sequence homology in the extracellular domains, their intracellular domains lack sequence homology, suggesting that they differ in their internal signal transduction pathways. TNF Receptor I contains an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein), and subsequent interactions with FADD. TNF Receptor I can also activate the transcription factor NFkB via TRAF2 (TNF Receptor associated factor 2). The cytoplasmic domain of TNF Receptor I can directly interact with Jak kinase, thereby activating the JAK/STAT signal transduction cascade. TNF Receptor I is expressed by virtually all nucleated mammalian cells, including hepatocytes, monocytes and neutrophils, cardiac muscle cells, endothelial cells, and CD34 + hematopoietic progenitors. Both TNF alpha and TNF beta bind to TNF Receptor I.Synonyms: TNF-R1, TNF-RI, TNFR-I, Tnfrsf1a, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor type I, p55, p60
- 基因ID
- 9606
- UniProt
- P19438
- 途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Hepatitis C, Ubiquitin Proteasome Pathway
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