TNFRSF10A 抗体
(6 references)-
- 抗原 See all TNFRSF10A 抗体
- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TNFRSF10A antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), Functional Studies (Func)
- 特异性
- Recognizes human TRAIL-R1.
- 交叉反应
- 人
- 交叉反应 （详细）
- Does not cross-react with human TRAIL-R2, -R3 or -R4.
- 纯化方法
- Purified from concentrated hybridoma tissue culture supernatant.
- 纯度
- >95 % (SDS-PAGE)
- 免疫原
- Recombinant human TRAIL-R1 (DR4).
- 克隆位点
- HS101
- 亚型
- IgG1
- Top Product
- Discover our top product TNFRSF10A Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) antibody
TNFRSF10A 适用: 人 FACS, IP, ICC 宿主: 小鼠 Monoclonal DR-4-02 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 269-468) antibodyTNFRSF10A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 269-468) antibodyTNFRSF10A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) antibody (FITC)TNFRSF10A 适用: 人 FACS 宿主: 小鼠 Monoclonal DR-4-02 FITC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) antibody (PE)TNFRSF10A 适用: 人 FACS 宿主: 小鼠 Monoclonal DR-4-02 PE
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 105-204) antibodyTNFRSF10A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) antibodyTNFRSF10A 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) antibodyTNFRSF10A 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (C-Term) antibodyTNFRSF10A 适用: 人 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 1-20) antibodyTNFRSF10A 适用: 人 WB, FACS, ICC, IF 宿主: 小鼠 Monoclonal 32A1380 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - 有效期
- 12 months
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: "TRAIL regulates normal erythroid maturation through an ERK-dependent pathway." in: Blood, Vol. 103, Issue 2, pp. 517-22, (2004) (PubMed).
: "IFNalpha-stimulated neutrophils and monocytes release a soluble form of TNF-related apoptosis-inducing ligand (TRAIL/Apo-2 ligand) displaying apoptotic activity on leukemic cells." in: Blood, Vol. 103, Issue 10, pp. 3837-44, (2004) (PubMed).
: "Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs." in: Cell death and differentiation, Vol. 11 Suppl 1, pp. S86-96, (2004) (PubMed).
: "Proteasome inhibition results in TRAIL sensitization of primary keratinocytes by removing the resistance-mediating block of effector caspase maturation." in: Molecular and cellular biology, Vol. 23, Issue 3, pp. 777-90, (2003) (PubMed).
: "TNF-related apoptosis-inducing ligand mediates tumoricidal activity of human monocytes stimulated by Newcastle disease virus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 4, pp. 1814-21, (2003) (PubMed).
: "Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8." in: The EMBO journal, Vol. 21, Issue 17, pp. 4520-30, (2002) (PubMed).
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: "TRAIL regulates normal erythroid maturation through an ERK-dependent pathway." in: Blood, Vol. 103, Issue 2, pp. 517-22, (2004) (PubMed).
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- 抗原
- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
- 别名
- TRAIL-R1 (TNFRSF10A 产品)
- 别名
- APO2 antibody, CD261 antibody, DR4 antibody, TRAILR-1 antibody, TRAILR1 antibody, TNFRSF10A antibody, TNF receptor superfamily member 10a antibody, tumor necrosis factor receptor superfamily member 26 antibody, tumor necrosis factor receptor superfamily, member 10a antibody, TNFRSF10A antibody, LOC510798 antibody
- 背景
- TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
- UniProt
- O00220
- 途径
- Apoptosis, Positive Regulation of Endopeptidase Activity
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