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TNFRSF10A 抗体
TNFRSF10A
适用: 人
FACS, IP, ICC, Func
宿主: 小鼠
Monoclonal
HS101
unconjugated
TNFRSF10A抗体详情
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抗原
See all TNFRSF10A 抗体
TNFRSF10A
(Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
适用
All reactivities for TNFRSF10A 抗体
人
宿主
All hosts for TNFRSF10A 抗体
小鼠
克隆类型
All clonalities for TNFRSF10A 抗体
单克隆
标记
All conjugates for TNFRSF10A 抗体
This TNFRSF10A antibody is un-conjugated
应用范围
All applications for TNFRSF10A 抗体
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), Functional Studies (Func)
特异性
Recognizes human TRAIL-R1.
交叉反应
人
交叉反应 (详细)
Does not cross-react with human TRAIL-R2, -R3 or -R4.
纯化方法
Purified from concentrated hybridoma tissue culture supernatant.
纯度
>95 % (SDS-PAGE)
免疫原
Recombinant human TRAIL-R1 (DR4).
克隆位点
HS101
亚型
IgG1
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Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
Lot specific
缓冲液
In PBS containing 10 % glycerol.
储存液
Without preservative
储存条件
4 °C,-20 °C
储存方法
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C.
有效期
12 months
TNFRSF10A目标详情
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抗原
TNFRSF10A
(Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
别名
TRAIL-R1 (TNFRSF10A 产品 )
别名
APO2 antibody, CD261 antibody, DR4 antibody, TRAILR-1 antibody, TRAILR1 antibody, TNFRSF10A antibody, TNF receptor superfamily member 10a antibody, tumor necrosis factor receptor superfamily member 26 antibody, tumor necrosis factor receptor superfamily, member 10a antibody, TNFRSF10A antibody, LOC510798 antibody
背景
TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
UniProt
O00220
途径
Apoptosis , Positive Regulation of Endopeptidase Activity
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