CIITA
适用: 人
WB, ELISA, IP
宿主: 小鼠
Monoclonal
unconjugated
应用备注
Suitable for Immunoblotting (1/500), ELISA and Immunoprecipitation. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
状态
Liquid
浓度
90.0 mg/mL (by Refractometry)
注意事项
Avoid repeated freezing or thawing.
储存条件
4 °C/-20 °C
储存方法
Store original vial at 2-8 °C. After reconstitution store stock solution at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.
抗原
CIITA
(Class II, Major Histocompatibility Complex, Transactivator (CIITA))
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背景
The transactivator CIITA regulates basal and interferon-induced expression of Major Histocompatibility Complex class II genes. CIITA restores expression of all MHC class II gene expression in mutant cells and corrects regulatory defects of MHC class II genes. Antibodies to this transactivator are useful in the study of diseases of pathological MHC class II expression. Antigen can be obtained from Raji cell lysates. Typically levels of CIITA expression are too low to detect endogenous levels of protein expression. Transiently transfected cells are usually employed to study this transcription factor.Synonyms: MHC class II transactivator, MHC2TA