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IL-6 抗体 (Biotin)

The 山羊 多克隆 anti-IL-6 antibody is suitable to detect IL-6 in samples from 人. It has been validated for WB 和 EIA.
产品编号 ABIN116081
发货至: 中国
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中国
北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL-6 抗体 (Biotin) (ABIN116081)

抗原

See all IL-6 (IL6) 抗体
IL-6 (IL6) (Interleukin 6 (IL6))

适用

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宿主

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山羊

克隆类型

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多克隆

标记

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This IL-6 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects Interleukin-6.

    纯化方法

    Affinity chromatograophy

    免疫原

    Highly pure (> 98 %) recombinant human IL-6
  • 应用备注

    ELISA: Direct: To detect hIL-6 (using 100 μL/well antibody solution) a concentration of0.25 - 1.0 μg/mL of this antibody is required. In conjunction with compatible secondaryreagents, it allows the detection of at least 0.2 - 0.4 ng/well of recombinant hIL-6. Sandwich: To detect hIL-6 (using 100 μL/well antibody solution) a concentration of0.25 - 1.0 μg/mL of this antibody is required. In conjunction with Polyclonal Anti-Human IL-6as a capture antibody, it allows the detection of at least 0.2 - 0.4 ng/well of recombinanthIL-6. Western blot: To detect hIL-6 this antibody can be used at a concentration of 0.1 - 0.2g/mL. Used in conjunction with compatible secondary reagents the detection limit for

    限制

    仅限研究用
  • 溶解方式

    Centrifuge vial prior to opening. Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1 - 1.0 mg/mL.

    缓冲液

    PBS, pH 7.2

    注意事项

    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • 抗原

    IL-6 (IL6) (Interleukin 6 (IL6))

    别名

    Interleukin-6 (IL6)

    背景

    Interleukin 6 (IL6) is a multifunctional 24 kDa protein originally discovered in the medium of RNA stimulated fibroblastoid cells. It is upregulated by IL1, TNF, PDGF, IFN beta, TNF alpha, NGF, IL17 and downregulated by glucocorticoids IL4, TGF beta. IL6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be as important as IL1 and TNF alpha in regulating the acute phase response. IL6 has also been implicated in regulating adipose mass. IL6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages and endothelial cells. It acts upon a variety of cells including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. In addition, IL6 appears to interact with IL2 in the proliferation of T lymphocytes. IL6 potentiates the proliferative effect of IL3 on multipotential hematopoietic progenitors.Synonyms: B-cell stimulatory factor 2, BSF-2, CDF, CTL differentiation factor, Hybridoma growth factor, IFNB2, IL-6, Interferon beta-2

    基因ID

    3569

    NCBI登录号

    NP_000591

    UniProt

    P05231

    途径

    TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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