IL-1 beta 抗体
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北京 101111
Quick Overview for IL-1 beta 抗体 (ABIN114529)
抗原
See all IL-1 beta (IL1B) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Reactive with natural and recombinant human IL-1β. Does not show any cross reaction with recombinant human IL-1α, recombinant murine IL-1α or IL-1β.
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纯化方法
- Protein G affinity purified
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免疫原
- Purified recombinant human IL-1beta
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亚型
- IgG1
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应用备注
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ELISA. Western Blot: An antibody concentration of 20-100 ng/mL will allow visualization of 100 ng/lane of human IL-1β.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with double distillated water is recommended to adjust the final concentration to 1.00 mg/mL
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缓冲液
- 0.01 M PBS, pH 7.2
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注意事项
- Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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别名
- Interleukin-1 beta / IL-1B
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背景
- Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25 % homology in their amino acid sequence.Synonyms: Catabolin, IL-1 beta, IL1 beta, IL1B, IL1F2
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基因ID
- 3553
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NCBI登录号
- NP_000567
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UniProt
- P01584
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途径
- NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
抗原
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