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CD45 抗体 (APC)

Name: CD45 抗体 (APC)
Brand: antibodies-online
SKU: ABIN1112150
Availability: OutOfStock

PTPRC 适用: 人 FACS, IHC, IF 宿主: 小鼠 Monoclonal HI30 APC

(2 references)

产品编号 ABIN1112150

发货至: 中国

Datasheet as PDF

抗原 See all CD45 (PTPRC) 抗体

CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
适用
347

208

79

29

20

16

15

10

7

6

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3

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1

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1
人
宿主
245

160

137

2

1

1
小鼠
Compatible Secondaries
克隆类型
410

128

1
单克隆
标记
165

52

44

43

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13

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11

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This CD45 antibody is conjugated to APC
应用范围
444

187

146

119

91

58

43

39

38

27

15

14

13

12

9

5

4

3

3

2

2

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1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

产品特性

Monoclonal Mouse Anti-Human CD45 is recommended for use in flow cytometry for identification and analysis of CD45 cells.

克隆位点

HI30

亚型

IgG1

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anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 24-575) antibody
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anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibody
PTPRC 适用: 人 FACS, IHC, WB, IF, StM 宿主: 兔 Monoclonal PTPRC-2877R unconjugated Recombinant Antibody

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibody
PTPRC 适用: 人 FACS, WB, IP, IHC (p), ICC 宿主: 小鼠 Monoclonal MEM-28 unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 378-577) antibody
PTPRC 适用: 人, 小鼠, 大鼠 FACS, IHC, WB, ELISA, ICC 宿主: 小鼠 Monoclonal 2H3E2 unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 431-577) antibody
PTPRC 适用: 人 FACS, IHC, WB, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 7C9F12 unconjugated

应用备注

It is recommended for use in flow cytometry and imunohistochemistry reagent is effective for direct immunofluorescence staining of human tissue for flow cytometric analysis using 20 µl/10^6 cells.

说明

Allophycocyanin (APC), Abs/Em: 651/662 nm.

限制

仅限研究用
状态

Liquid

缓冲液

The conjugate is provided in liquid form in buffer containing and Antibody Stabilizer solution, PBS 20 mM, pH 7,4.

储存液

Sodium azide

注意事项

1. The device is not intended for clinical use including diagnosis, prognosis, and monitoring of a disease state, and it must not be used in conjunction with patient records or treatment. 2. This product contains Sodium azide (NaN3), a chemical highly toxic in pure form. At product concentrations, though not classified as hazardous, Sodium azide may react with lead and copper plumbing to form highly explosive build-ups of metal azides. Upon disposal, flush with large volumes of water to prevent metal azide build-up in plumbing. 3. As with any product derived from biological sources, proper handling procedures should be used.

储存条件

4 °C
Song, Ara, Wu, Woo, Reynolds, Seeger, DeClerck, Thiele, Sposto, Metelitsa: "Oncogene MYCN regulates localization of NKT cells to the site of disease in neuroblastoma." in: The Journal of clinical investigation, Vol. 117, Issue 9, pp. 2702-12, (2007) (PubMed).

Leone, Rutella, Bonanno, Abbate, Rebuzzi, Giovannini, Lombardi, Galiuto, Liuzzo, Andreotti, Lanza, Contemi, Leone, Crea: "Mobilization of bone marrow-derived stem cells after myocardial infarction and left ventricular function." in: European heart journal, Vol. 26, Issue 12, pp. 1196-204, (2005) (PubMed).
抗原

CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))

别名

CD45 (PTPRC 产品)

别名

PTPRC antibody, si:dkeyp-47c5.1 antibody, B220 antibody, CD45 antibody, CD45R antibody, GP180 antibody, L-CA antibody, LCA antibody, LY5 antibody, T200 antibody, Cd45 antibody, Ly-5 antibody, Lyt-4 antibody, loc antibody, Lca antibody, RT7 antibody, cd45 antibody, protein tyrosine phosphatase, receptor type C antibody, protein tyrosine phosphatase, receptor type, C antibody, receptor-type tyrosine-protein phosphatase C antibody, PTPRC antibody, ptprc antibody, LOC100074271 antibody, Ptprc antibody

背景

CD45 is a 180-240 kDa single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA), B220, and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.

途径

TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling