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CD44 抗体 (APC)

CD44 适用: 人 FACS, IF Monoclonal HI44a APC
产品编号 ABIN1112149
发货至: 中国
  • 抗原 See all CD44 抗体
    CD44
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    克隆类型
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    单克隆
    标记
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    This CD44 antibody is conjugated to APC
    应用范围
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    Flow Cytometry (FACS), Immunofluorescence (IF)
    免疫原
    Peripheral Blood Mononuclear cells Positive control: Peripheral Blood from a healthy donor.
    克隆位点
    HI44a
    亚型
    IgG1
    Top Product
    Discover our top product CD44 Primary Antibody
  • 应用备注
    It is recommended for use in flow cytometry. This reagent is effective for direct immunofluorescence staining of human tissue for flow cytometric analysis using 20 µl/10^6 cells.
    说明

    Allophycocyanin (Febico, Far East Bio-Tech Co.).

    限制
    仅限研究用
  • 储存条件
    4 °C
  • 抗原
    CD44
    别名
    CD44 (CD44 产品)
    别名
    CDW44 antibody, CSPG8 antibody, ECMR-III antibody, HCELL antibody, HUTCH-I antibody, IN antibody, LHR antibody, MC56 antibody, MDU2 antibody, MDU3 antibody, MIC4 antibody, Pgp1 antibody, AU023126 antibody, AW121933 antibody, AW146109 antibody, HERMES antibody, Ly-24 antibody, Pgp-1 antibody, CD44A antibody, METAA antibody, RHAMM antibody, XCD44 antibody, cd44 antibody, cdw44 antibody, cspg8 antibody, ecmr-iii antibody, hcell antibody, lhr antibody, mc56 antibody, mdu2 antibody, mdu3 antibody, mic4 antibody, mutch-i antibody, pgp1 antibody, CD44 molecule (Indian blood group) antibody, syndecan 4 antibody, CD44 antigen antibody, CD44 molecule (Indian blood group) S homeolog antibody, CD44 antibody, SDC4 antibody, Cd44 antibody, cd44.S antibody
    背景
    The mature CD44 antigen is a transmembranous molecule which has undergone both extensive O-linked and N-linked glycosylation. The main cellular reactivity is on leucocytes and red blood cells with only weak reactivity on platelets. CD44 antigen is widely expressed on most cell types including leukocytes, erythrocytes, endothelial cells and epithelial cells, but not on platelets. CD44 is involved in leukocyte attaching and rolling on endothelial cells, homing to peripheral lymphoid organs and sites of inflammation, and leukocyte aggregation. CD44 HI44a recognizes a cell-surface glycoprotein that exists in a variety of isoforms. It is synthesized as a molecule of Mr 37 kDa s (kDa). Upon glycosylation, it is converted to an 80- to 95-kDa form. Alternatively, a 180- to 200-kDa form results from the addition of chondroitin sulfate. The CD44 antigen is present on approximately 90% of lymphocytes, monocytes, and granulocytes and in lower amounts on thymocytes, fibroblasts, and erythrocytes. The antigen mediates a variety of functions, including leucocyte-endothelial cell binding and lymphocyte homing to cer-tain peripheral lymphoid microenvironments.
    途径
    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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