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PKC alpha 抗体 (C-Term)

Name: PKC alpha 抗体 (C-Term)
SKU: ABIN1108731
Availability: OutOfStock

PKCa 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Western blot analysis of Hela cell lysis with PKCalpha antibody (PKC alpha 抗体 (C-Term))

Staining with PRKCA antibody (PKC alpha 抗体 (C-Term))

IHC (p)

2 images

产品编号 ABIN1108731

发货至: 中国

Datasheet as PDF

抗原 See all PKC alpha (PKCa) 抗体

PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))
抗原表位
24

20

18

12

11

10

8

7

7

6

6

5

5

5

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
178

90

68

6

5

5

3

2

2

1

1

1

1
人, 小鼠, 大鼠
宿主
174

12

1
兔
Compatible Secondaries
克隆类型
140

46
多克隆
标记
96

15

13

6

6

6

6

6

6

6

6

6

2

2

1

1

1

1

1
This PKC alpha antibody is un-conjugated
应用范围
128

71

53

33

22

20

17

15

14

8

5

2

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

特异性

This antibody detects PRKCA (C-term).

交叉反应（详细）

Species reactivity (tested):Human, mouse, rat.

纯化方法

Immunogen affinity purified

免疫原

Synthetic peptide corresponding to the C-terminal of human PKCa .Remarks: Sequence is identical to the related rat and mouse sequence.

亚型

IgG

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anti-Protein Kinase C, alpha (PKCa) (pThr638) antibody
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anti-Protein Kinase C, alpha (PKCa) antibody
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PKCa 适用: 人 WB, FACS, IHC (p), IF 宿主: 兔 Polyclonal RB01012 unconjugated

anti-Protein Kinase C, alpha (PKCa) (C-Term) antibody
PKCa 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, alpha (PKCa) (C-Term) antibody
PKCa 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, alpha (PKCa) (N-Term) antibody
PKCa 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
溶解方式

0.2 mL of distilled water will yield a concentration of 500 μg/mL.

缓冲液

5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

储存液

Sodium azide, Thimerosal (Merthiolate)

注意事项

This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
抗原

PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))

别名

PRKCA (PKCa 产品)

别名

pkc-alpha antibody, pkcalpha antibody, im:7139045 antibody, si:dkey-8l19.1 antibody, LOC100219195 antibody, AAG6 antibody, PKC-alpha antibody, PKCA antibody, PRKACA antibody, AI875142 antibody, Pkca antibody, PKRCA antibody, protein kinase C alpha antibody, protein kinase C, alpha L homeolog antibody, protein kinase C, alpha antibody, PRKCA antibody, prkca.L antibody, prkca antibody, Prkca antibody

背景

Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms (α, βI, βII andγ) and novel (n) PKC isoforms (δ,ε,ζ,ηandθ). Patterns of expression for each PKC isoform differs among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC and are independent of Ca2+ On the other hand, nPKC and , as well as all of the cPKC members, possess phorbol ester-binding activities and kinase activities.Synonyms: PKC alpha, PKC-A, PKC-alpha, PKCA, PRKACA, Protein kinase C alpha type

基因ID

5578

NCBI登录号

NP_002728

UniProt

P17252

途径

WNT signaling, TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling