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p53 抗体
TP53
适用: 人
WB, IF, IHC (p), IHC (fro)
宿主: 小鼠
Monoclonal
IMD-53
unconjugated
p53抗体详情
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抗原
See all p53 (TP53) 抗体
p53 (TP53)
(Tumor Protein P53 (TP53))
适用
All reactivities for p53 抗体
人
宿主
All hosts for p53 抗体
小鼠
克隆类型
All clonalities for p53 抗体
单克隆
标记
All conjugates for p53 抗体
This p53 antibody is un-conjugated
应用范围
All applications for p53 抗体
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
特异性
This antibody reacts to p53 (TP53).
纯化方法
Affinity Chromatography
免疫原
Recombinant Human wild-type p53 protein.
克隆位点
IMD-53
亚型
IgG2a
Top Product
Discover our top product TP53 Primary Antibody
Alternatives
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anti-Tumor Protein P53 (TP53) (AA 301-393) antibody
TP53
适用: 人, 小鼠, 大鼠, 山羊
WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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溶解方式
Restore with 1.2 % Sodium Acetate or neutral PBS
浓度
0.1 mg/mL
缓冲液
1.2 % Sodium Acetate with 2 mg BSA and 0.01 mg Sodium Azide as preservative
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
-20 °C
储存方法
Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
p53目标详情
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抗原
p53 (TP53)
(Tumor Protein P53 (TP53))
别名
p53 (TP53) (TP53 产品 )
别名
BCC7 antibody, LFS1 antibody, P53 antibody, TRP53 antibody, p53 antibody, Trp53 antibody, brp53 antibody, drp53 antibody, etID22686.5 antibody, fb40d06 antibody, wu:fb40d06 antibody, zgc:111919 antibody, Tp53 antibody, bbl antibody, bfy antibody, bhy antibody, p44 antibody, tp53 antibody, Xp53 antibody, TP53 antibody, tumor protein p53 antibody, cellular tumor antigen p53 antibody, transformation related protein 53 antibody, tumor protein p53 L homeolog antibody, TP53 antibody, CpipJ_CPIJ002758 antibody, Tp53 antibody, tp53 antibody, Trp53 antibody, tp53.L antibody
背景
The p53 tumor antigen is found in increased amounts in a wide variety of transformed cells. The protein is also detectable in many actively proliferating, nontransformed cells, but it is undetectable or present at low levels in resting cells. This protein induces cell cycle arrest or apoptosis in response to sublethal or severe DNA damage, respectively, by differential transcription of target genes and through transcription-independent apoptotic functions. The p53 protein contains 393 amino acids. Human p53 tumour antigen is Locatedto band 17p13. p53 mutations are common in pancreatic cancer and are absent in chronic pancreatitis.Synonyms: Cellular tumor antigen p53, NY-CO-13, Phosphoprotein p53, Tumor suppressor p53
基因ID
7157
NCBI登录号
NP_000537
UniProt
P04637
途径
p53 Pathway , MAPK Pathway , PI3K-Akt Signaling , Apoptosis , AMPK Signaling , Chromatin Binding , ER-Nucleus Signaling , Positive Regulation of Endopeptidase Activity , Hepatitis C , Protein targeting to Nucleus , Autophagy , Warburg Effect
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