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Interleukin 17a 抗体

IL17A 适用: 人 Func 宿主: 小鼠 Monoclonal B-B51 unconjugated
产品编号 ABIN1107806
发货至: 中国
  • 抗原 See all Interleukin 17a (IL17A) 抗体
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    适用
    • 88
    • 41
    • 19
    • 7
    • 6
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    宿主
    • 62
    • 38
    • 16
    • 7
    • 3
    小鼠
    克隆类型
    • 71
    • 54
    • 1
    单克隆
    标记
    • 60
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    This Interleukin 17a antibody is un-conjugated
    应用范围
    • 70
    • 59
    • 29
    • 14
    • 11
    • 11
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    • 5
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    • 1
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    Functional Studies (Func)
    特异性
    This antibody recognizes both recombinant and natural IL-17A.
    纯化方法
    Ion Exchange Chromatography
    过滤
    0.22 μm filtered
    免疫原
    Recombinant Human IL-17A.
    克隆位点
    B-B51
    亚型
    IgG2b
    Top Product
    Discover our top product IL17A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate-buffered saline. Sterile-filtered through 0.22 μm and treated to remove endotoxins. Carrier and preservative free.
    储存液
    Without preservative
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    别名
    Interleukin-17A (IL17A) (IL17A 产品)
    别名
    CTLA8 antibody, IL-17 antibody, IL-17A antibody, IL17 antibody, Ctla-8 antibody, Ctla8 antibody, Il17 antibody, ChIL-17 antibody, IL-17F antibody, IL17A antibody, CTLA-8 antibody, interleukin 17A antibody, IL17A antibody, Il17a antibody
    背景
    Interleukin 17 (IL-17) is a pro-inflammatory cytokine produced by a subset of T helper cells that develops distinct from the Th1- and Th2- cell differentiation pathways. IL-17, also known as CTLA-8, stimulates induction of other pro-inflammatory cytokines TNF alpha, IL-1 beta, IL-6, and IL-8, and reports strongly suggest the involvement of IL-17 in several chronic inflammatory diseases such as rheumatoid arthritis, psoriasis and multiple sclerosis. TGF-ß (differentiation) and IL-23 (expansion) are required for induction and maintenance of Th17 (IL-17 producing) cells, which in turn induce the other pro-inflammatory cytokines. IL-17 (~32 kDa) protein is produced and exists as a homo-dimer, has homology to a herpes virus early protein, is one of the six members (IL-17A-F) of this cytokine family, and is well characterzed and highly expressed by activated effector memory T cells.Synonyms: CTLA-8, CTLA8, Cytotoxic T-lymphocyte-associated antigen 8, IL-17, IL-17A, IL17
    基因ID
    3605
    NCBI登录号
    NP_002181
    UniProt
    Q16552
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