HLA-DMA 抗体 (FITC)
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- 抗原 See all HLA-DMA 抗体
- HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This HLA-DMA antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The antibody M5/114 reacts with murine MHC class II glycoproteins. It recognizes a shared determinant on I-Ab, I-Ad, I-Aq, and I-Ed, I-Ek alloantigens, but it does not react with I-Af, I-Ak, I-As. This antibody can inhibit I-A-restricted T cell responses of the H-2b, H-2d, H-2q, H-2u but not H-2f, H-2k, H-2s haplotypes.
- 交叉反应 (详细)
- Species reactivity (tested):Mouse
- 免疫原
- Activated C57BL/6 mouse spleen cells
- 克隆位点
- M5-114
- 亚型
- IgG2b
- Top Product
- Discover our top product HLA-DMA Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), approx. pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE! This product is photosensitive and should be protected from light.
- 储存条件
- 4 °C
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- 抗原
- HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))
- Abstract
- HLA-DMA 产品
- 别名
- RT1.Ma antibody, RT1.DMa antibody, HLA-DMA antibody, H-2Ma antibody, H2-Ma antibody, D6S222E antibody, DMA antibody, HLADM antibody, RING6 antibody, RT1 class II, locus DMa antibody, SLA-DM alpha chain antibody, major histocompatibility complex, class II, DM alpha antibody, histocompatibility 2, class II, locus DMa antibody, RT1-DMa antibody, SLA-DMA antibody, DLA-DMA antibody, H2-DMa antibody, HLA-DMA antibody
- 背景
- MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long.Synonyms: DM alpha chain, DMA, HLA class II histocompatibility antigen, MHC class II antigen DMA, RING6, Really interesting new gene 6 protein
- 基因ID
- 3108
- NCBI登录号
- NP_006111
- UniProt
- P28067
- 途径
- Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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