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Glucocorticoid Receptor 抗体 (C-Term)

NR3C1 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1107374
发货至: 中国
  • 抗原 See all Glucocorticoid Receptor (NR3C1) 抗体
    Glucocorticoid Receptor (NR3C1) (Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1))
    抗原表位
    • 21
    • 17
    • 16
    • 13
    • 13
    • 7
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    C-Term
    适用
    • 161
    • 89
    • 64
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
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    人, 小鼠, 大鼠
    宿主
    • 157
    • 15
    • 3
    克隆类型
    • 147
    • 28
    多克隆
    标记
    • 78
    • 20
    • 14
    • 10
    • 8
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
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    • 3
    • 3
    This Glucocorticoid Receptor antibody is un-conjugated
    应用范围
    • 159
    • 74
    • 61
    • 43
    • 39
    • 39
    • 35
    • 25
    • 25
    • 16
    • 10
    • 5
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody detects Glucocorticoid receptor (C-term). No cross reactivity with other proteins.
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse, Rat.
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    Synthetic peptide corresponding to a sequence at the C-terminal of Human GR .Remarks: Sequence is identical to the related Rat and Mouse sequence.
    亚型
    IgG
    Top Product
    Discover our top product NR3C1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    Restore with 0.2 mL of distilled water to yield a concentration of 0.5 mg/mL.
    浓度
    0.5 mg/mL
    缓冲液
    5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg Sodium Azide
    储存液
    Sodium azide, Thimerosal (Merthiolate)
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody after reconstitution at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Glucocorticoid Receptor (NR3C1) (Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1))
    别名
    Glucocorticoid Receptor (NR3C1 产品)
    别名
    GR antibody, gcr antibody, grl antibody, xGR antibody, gccr antibody, gr antibody, zgc:113038 antibody, NR3C1 antibody, GCL antibody, LOC100302444 antibody, Gcr antibody, Grl antibody, Grl-1 antibody, Grl1 antibody, GRL antibody, GCCR antibody, GCR antibody, NO antibody, GR-A antibody, nr3c1 antibody, nuclear receptor subfamily 3 group C member 1 antibody, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) antibody, nuclear receptor subfamily 3, group C, member 1 antibody, glucocorticoid receptor antibody, NR3C1 antibody, nr3c1 antibody, LOC100302444 antibody, Nr3c1 antibody
    背景
    Glucocorticoid receptor(GR) maps to the distal long arm of chromosome 5. The human glucocorticoid receptor (hGR) gene contains a total of 10 exons and has a minimum size of 80 kilobases. The identification of complementary DNAs encoding the human glucocorticoid receptor (hGR) predicts two protein forms (alpha and beta, 777 and 742 amino acids long, respectively) which differ at their carboxy termini and both forms of the receptor are related, with respect to their domain structure, to the v-erb-A oncogene product of avian erythroblastosis virus (AEV), which suggests that steroid receptor genes and the c-erb-A proto-oncogene are derived from a common primordial regulatory gene. Transcriptional regulation by the glucocorticoid receptor (GR) is mediated by hormone binding, receptor dimerization, and coactivator recruitment.Synonyms: GR, GRL, NR3C1
    基因ID
    2908
    NCBI登录号
    NP_000167
    UniProt
    P04150
    途径
    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Regulation of Carbohydrate Metabolic Process
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