Complement Factor I 抗体
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- 抗原 See all Complement Factor I (CFI) 抗体
- Complement Factor I (CFI)
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Complement Factor I antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- Reacts with 65 kDa CFI protein.
- 交叉反应 (详细)
- Species reactivity (tested):Human.
- 纯化方法
- Affinity Chromatography on Protein A
- 免疫原
- Synthetic peptide derived from an internal domain of Human CFI
- Top Product
- Discover our top product CFI Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 溶解方式
- Restore in distilled water.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Complement Factor I (CFI)
- 别名
- Complement Factor I (CFI 产品)
- 别名
- cfi antibody, MGC53615 antibody, Cfi antibody, factor I antibody, IF antibody, gb:ai721528 antibody, ahus3 antibody, c3b-ina antibody, c3bc4bi antibody, c3bina antibody, kaf antibody, CFI antibody, AHUS3 antibody, C3BINA antibody, C3b-INA antibody, FI antibody, KAF antibody, complement factor I S homeolog antibody, complement factor I L homeolog antibody, complement factor I antibody, complement component factor i antibody, cfi.S antibody, cfi.L antibody, CFI antibody, cfi antibody, Cfi antibody
- 背景
- Defects in CFI are a cause of susceptibility to hemolytic uremic syndrome atypical type 3 (AHUS3) [MIM:612923]. An atypical form of hemolytic uremic syndrome. It is a complex genetic disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, renal failure and absence of episodes of enterocolitis and diarrhea. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease. Note=Susceptibility to the development of atypical hemolytic uremic syndrome can be conferred by mutations in various components of or regulatory factors in the complement cascade system. Other genes may play a role in modifying the phenotype. Defects in CFI are the cause of complement factor I deficiency (CFI deficiency) [MIM:610984]. CFI deficiency is an autosomal recessive condition associated with a propensity to pyogenic infections.Synonyms: AHUS3, C3B/C4B inactivator, C3BINA, C3b-INA, CFI, IF, KAF
- 基因ID
- 3426
- NCBI登录号
- NP_000195
- 途径
- Complement System
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