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CHEK1 抗体

This anti-CHEK1 antibody is a 小鼠 单克隆 antibody detecting CHEK1 in WB 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN1106682
发货至: 中国

Quick Overview for CHEK1 抗体 (ABIN1106682)

抗原

See all CHEK1 抗体
CHEK1 (Checkpoint Kinase 1 (CHEK1))

适用

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人, 小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This CHEK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

2G1D5
  • 交叉反应 (详细)

    Species reactivity (tested):Human, Mouse.

    纯化方法

    Purified

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS, 0.03 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    CHEK1 (Checkpoint Kinase 1 (CHEK1))

    别名

    CHK1

    背景

    CHK1, also known as CHEK1, it is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Cdc25, when phosphorylated on serine 216 by chk1 becomes bound by an adaptor protein in the cytoplasm. Therefore it is inhibited from removing the inhibiting phosphate from MPF (mitotic/maturation promoting factor) added by Wee1. Consequently, a cell is prevented from entering mitosis. Chk1 can also phosphorylate p53 at Ser20 in vitro.Synonyms: CHEK-1, CHEK1, CHK1 checkpoint homolog, Serine/threonine-protein kinase Chk1

    分子量

    56 kDa

    基因ID

    1111

    途径

    p53 Pathway, Apoptosis, Cell Division Cycle, DNA Damage Repair
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