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CHEK1 抗体

CHEK1 适用: 人, 小鼠 WB, EIA 宿主: 小鼠 Monoclonal 2G1D5 unconjugated
产品编号 ABIN1106682
发货至: 中国
  • 抗原 See all CHEK1 抗体
    CHEK1 (Checkpoint Kinase 1 (CHEK1))
    适用
    • 170
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    人, 小鼠
    宿主
    • 184
    • 11
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    • 5
    小鼠
    克隆类型
    • 185
    • 21
    单克隆
    标记
    • 112
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    This CHEK1 antibody is un-conjugated
    应用范围
    • 154
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    Western Blotting (WB), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse.
    纯化方法
    Purified
    克隆位点
    2G1D5
    亚型
    IgG1
    Top Product
    Discover our top product CHEK1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS, 0.03 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原
    CHEK1 (Checkpoint Kinase 1 (CHEK1))
    别名
    CHK1 (CHEK1 产品)
    背景
    CHK1, also known as CHEK1, it is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Cdc25, when phosphorylated on serine 216 by chk1 becomes bound by an adaptor protein in the cytoplasm. Therefore it is inhibited from removing the inhibiting phosphate from MPF (mitotic/maturation promoting factor) added by Wee1. Consequently, a cell is prevented from entering mitosis. Chk1 can also phosphorylate p53 at Ser20 in vitro.Synonyms: CHEK-1, CHEK1, CHK1 checkpoint homolog, Serine/threonine-protein kinase Chk1
    分子量
    56 kDa
    基因ID
    1111
    途径
    p53 Pathway, Apoptosis, Cell Division Cycle, DNA Damage Repair
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