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TRAIL 抗体
TNFSF10
适用: 人
Func
宿主: 小鼠
Monoclonal
B-T24
unconjugated
TRAIL抗体详情
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抗原
See all TRAIL (TNFSF10) 抗体
TRAIL (TNFSF10)
(Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))
适用
All reactivities for TRAIL 抗体
人
宿主
All hosts for TRAIL 抗体
小鼠
克隆类型
All clonalities for TRAIL 抗体
单克隆
标记
All conjugates for TRAIL 抗体
This TRAIL antibody is un-conjugated
应用范围
All applications for TRAIL 抗体
Functional Studies (Func)
特异性
Recognizes the soluble antigen. Recognizes the TRAIL, APO2L antigen, a 32 kDa protein.
交叉反应 (详细)
Species reactivity (tested):Human.
纯化方法
Ion Exchange Chromatography.
过滤
0.22 μm filtered
免疫原
Recombinant Human TRAIL. Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells.
克隆位点
B-T24
亚型
IgG1
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Discover our top product TNFSF10 Primary Antibody
Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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浓度
1.0 mg/mL
缓冲液
Phosphate-buffered saline without Carrier and preservatives. This prodcut is sterile-filtered through 0.22 μm and treated to remove Endotoxins.
储存液
Without preservative
储存条件
4 °C
储存方法
Store the antibody undiluted at 2-8 °C.
TRAIL目标详情
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抗原
TRAIL (TNFSF10)
(Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))
别名
CD253 / TRAIL (TNFSF10 产品 )
别名
APO2L antibody, Apo-2L antibody, CD253 antibody, TL2 antibody, TRAIL antibody, A330042I21Rik antibody, AI448571 antibody, APO-2L antibody, Ly81 antibody, Trail antibody, tl2 antibody, apo2l antibody, cd253 antibody, trail antibody, apo-2l antibody, trail1 antibody, xtrail1 antibody, tnfsf10l2 antibody, zgc:92320 antibody, TNLG6A antibody, TNF superfamily member 10 antibody, tumor necrosis factor (ligand) superfamily, member 10 antibody, tumor necrosis factor superfamily member 10 antibody, TNF superfamily member 10 S homeolog antibody, TNFSF10 antibody, Tnfsf10 antibody, tnfsf10.S antibody, tnfsf10 antibody
背景
TRAIL (TNF-related apoptosis-inducing ligand), a member of the TNF ligand family, is a type II membrane protein and expressed in a variety of human tissues. Two death domains containing receptors DR4 and DR5 have been identified as the receptors for TRAIL and two decoy receptors designated DcR1 and DcR2 inhibit TRAIL function. The multiple receptors suggest a complex role for regulation of signaling by the cytokine. TRAIL induces apoptosis and NF-kB activation in many tissues and cells.Synonyms: APO2L, Apo-2 ligand, Apo-2L, TNF-related apoptosis-inducing ligand, TNFSF10, Tumor necrosis factor ligand superfamily member 10
基因ID
8743
NCBI登录号
NP_003801
UniProt
P50591
途径
Apoptosis , Positive Regulation of Endopeptidase Activity
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