TNFRSF1A 抗体 (Extracellular Domain)
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- 抗原 See all TNFRSF1A 抗体
- TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
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抗原表位
- Extracellular Domain
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适用
- 小鼠
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宿主
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仓鼠
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克隆类型
- 单克隆
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标记
- This TNFRSF1A antibody is un-conjugated
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应用范围
- Immunoprecipitation (IP), Enzyme Immunoassay (EIA), Functional Studies (Func)
- 交叉反应 （详细）
- Species reactivity (tested):Mouse
- 纯化方法
- Purified
- 免疫原
- Purified soluble extracellular domain of mouse TNF-RI
- 克隆位点
- 55R-170
- 亚型
- IgG
- Top Product
- Discover our top product TNFRSF1A Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 248-428) antibody
TNFRSF1A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 22-211) antibodyTNFRSF1A 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibodyTNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (HRP)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal HRP
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (FITC)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal FITC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (Alkaline Phosphatase (AP))TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal Alkaline Phosphatase (AP)
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (Biotin)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal Biotin
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (PE)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal PE
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (APC)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal APC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (PerCP)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal PerCP
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.1 mg/mL
- 缓冲液
- PBS, 1 % bovine serum albumin
- 储存条件
- 4 °C
- 储存方法
- Store at 2 - 8 °C.
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- 抗原
- TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
- 别名
- CD120a / TNFR1 (TNFRSF1A 产品)
- 别名
- CD120a antibody, FPF antibody, MS5 antibody, TBP1 antibody, TNF-R antibody, TNF-R-I antibody, TNF-R55 antibody, TNFAR antibody, TNFR1 antibody, TNFR1-d2 antibody, TNFR55 antibody, TNFR60 antibody, p55 antibody, p55-R antibody, p60 antibody, TNF-R1 antibody, TNF-alphaR1 antibody, TNFRI antibody, TNFRp55 antibody, TNFalpha-R1 antibody, Tnfr-2 antibody, Tnfr1 antibody, fpf antibody, tbp1 antibody, p55-r antibody, tnf-r antibody, tnfar antibody, tnfr1 antibody, cd120a antibody, tnfr55 antibody, tnfr60 antibody, xtnfr1 antibody, wu:fj65b10 antibody, zgc:85914 antibody, TNFR I antibody, TNFRSF1A antibody, TNFA antibody, cTNF antibody, TNF receptor superfamily member 1A antibody, tumor necrosis factor receptor superfamily, member 1a antibody, TNF receptor superfamily member 1A S homeolog antibody, tumor necrosis factor antibody, TNFRSF1A antibody, Tnfrsf1a antibody, tnfrsf1a.S antibody, tnfrsf1a antibody, TNF antibody
- 背景
- TNF-RI belongs to the large TNF receptor family, among which TNF-RII (TNF-R p75-80), lymphotoxin-beta receptor (LTbetaR) and the Herpes virus entry mediator (HVEM). Ligands for these receptors belong to the Tumor Necrosis Factor (TNF) superfamily of cytokines, which activate signaling pathways for cell survival, death, and differentiation that orchestrate the development, organization and homeostasis of lymphoid, mammary, neuronal and ectodermal tissues. TNF-RI contains a characteristic structural cassette termed death domain in its sequence that is conserved within a distinct subset of other TNF-R family members, such as CD95, DR3, DR4, and DR5. This death domain, was characterized as being essential for induction of apoptosis in vitro and has been structurally conserved within these TNF-R superfamily members. Deletion of the death domain of the TNF-RI results in a non-functional receptor, indicating that the death domain is required for the signal transduction of the physiological functions of TNF-RI in vivo. TNF-RI is a 55 kD type I transmembrane protein and is expressed on a variety of cell types at low levels. It is considered to play a prominent role in cell stimulation by TNF-alpha. Induction of cytotoxicity and other functions are mediated largely via TNF-RI. TNF-RI is present as soluble form in body fluids (for instance plasma and CSF). This extracellular TNF-RI is generated by two mechanisms, namely proteolytic cleavage of TNF-RI ectodomains and release of full-length TNF-RI in the membranes of exosome-like vesicles. TNF-RI and TNF-RII both interact with the homomeric forms of LTbeta or TNF. However, TNF-RI functions as the high affinity receptor for soluble TNF (sTNF). TNF-RI has been shown to be involved in a wide variety of inflammatory diseases, among which neurodegenerative diseases (Parkinson's and Alzheimer's disease), multiple sclerosis, asthma, atherosclerosis, rheumatology.Synonyms: TNF-R1, TNF-RI, TNFR-I, Tnfrsf1a, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor type I, p55, p60
- UniProt
- P25118
- 途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Hepatitis C, Ubiquitin Proteasome Pathway
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