PRICKLE1 抗体 (C-Term)
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- 抗原 See all PRICKLE1 抗体
- PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))
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抗原表位
- C-Term
- 适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRICKLE1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 特异性
- Multiple isoforms of PRICKLE1 are known to exist. PRICKLE1 antibody is predicted to not cross-react with other PRICKLE protein family members.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- PRICKLE1 antibody was raised against a AA 19 synthetic peptide near the carboxy terminus of human PRICKLE1.
- 亚型
- IgG
- Top Product
- Discover our top product PRICKLE1 Primary Antibody
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anti-Prickle-Like Protein 1 (PRICKLE1) (AA 684-756) antibody
PRICKLE1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8G5 unconjugated
anti-Prickle-Like Protein 1 (PRICKLE1) (AA 684-756) antibodyPRICKLE1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Prickle-Like Protein 1 (PRICKLE1) antibodyPRICKLE1 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Prickle-Like Protein 1 (PRICKLE1) (C-Term) antibodyPRICKLE1 适用: 人, 大鼠, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- PRICKLE1 antibody can be used for detection of PRICKLE1 by Western blot at 1 μg/mL. Antibody can also be used for immunofluorescence starting at 20 μg/mL. For immunofluorescence start at 20 μg/mL. Optimal dilutions for each application to be determined by the researcher.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- PRICKLE1 antibody can be stored at 4 °C for three months and -20 °C, stable for up to one year.
- 有效期
- 12 months
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- 抗原
- PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))
- 别名
- PRICKLE1 (PRICKLE1 产品)
- 别名
- EPM1B antibody, RILP antibody, Rilp antibody, 1110058P22Rik antibody, AW215793 antibody, Prickle antibody, mpk1 antibody, XPk antibody, pk-B antibody, prickle antibody, prickle-B antibody, Prickle-b antibody, prickle planar cell polarity protein 1 antibody, prickle planar cell polarity protein 1 L homeolog antibody, prickle planar cell polarity protein 1 S homeolog antibody, PRICKLE1 antibody, Prickle1 antibody, prickle1.L antibody, prickle1.S antibody
- 背景
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Synonyms:
REST, NRSF-interacting LIM domain protein 1, RILP, EPM1B
PRICKLE1 is a Disheveled-associated protein that serves as a nuclear translocation receptor for REST/NRSF and REST4. It contains three N-terminal LIM domains and three C-terminal nuclear localization signals. It localizes to the cytoplasm, as well as to the nuclear membrane and expressed at higher levels in placenta. PRICKLE1 is a negative regulator of the Wnt / beta-catenin signaling pathway and is a putative tumor suppressor in human HCCs. Defects in the gene encoding PRICKLE1 are associated with autosomal recessive progressive myoclonic epilepsy. - 基因ID
- 144165
- NCBI登录号
- NP_694571
- 途径
- WNT signaling, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development, Protein targeting to Nucleus
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