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PRICKLE1 抗体 (C-Term)

PRICKLE1 适用: 人, 大鼠, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1450074
发货至: 中国
  • 抗原 See all PRICKLE1 抗体
    PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))
    抗原表位
    • 15
    • 8
    • 7
    • 2
    C-Term
    适用
    人, 大鼠, 小鼠
    宿主
    • 31
    • 2
    克隆类型
    • 32
    • 1
    多克隆
    标记
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRICKLE1 antibody is un-conjugated
    应用范围
    • 18
    • 17
    • 13
    • 13
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse, Rat.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    19 amino acid synthetic peptide near the carboxy terminus of human PRICKLE1
    亚型
    IgG
    Top Product
    Discover our top product PRICKLE1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))
    别名
    PRICKLE1 (PRICKLE1 产品)
    别名
    EPM1B antibody, RILP antibody, Rilp antibody, 1110058P22Rik antibody, AW215793 antibody, Prickle antibody, mpk1 antibody, XPk antibody, pk-B antibody, prickle antibody, prickle-B antibody, Prickle-b antibody, prickle planar cell polarity protein 1 antibody, prickle planar cell polarity protein 1 L homeolog antibody, prickle planar cell polarity protein 1 S homeolog antibody, PRICKLE1 antibody, Prickle1 antibody, prickle1.L antibody, prickle1.S antibody
    背景
    PRICKLE1, also known as RILP or EPM1B, is a Disheveled-associated protein that serves as a nuclear translocation receptor for REST/NRSF and REST4 (1, 2). It contains three N-terminal LIM domains and three C-terminal nuclear localization signals. It localizes to the cytoplasm, as well as to the nuclear membrane and expressed at higher levels in placenta. PRICKLE1 is a negative regulator of the Wnt / beta-catenin signaling pathway and is a putative tumor suppressor in human HCCs. Defects in the gene encoding PRICKLE1 are associated with autosomal recessive progressive myoclonic epilepsy.Synonyms: PRICKLE-1, Prickle-like protein 1, REST/NRSF-interacting LIM domain protein 1, RILP
    基因ID
    144165
    NCBI登录号
    NP_694571
    途径
    WNT signaling, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development, Protein targeting to Nucleus
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