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- 抗原 See all PPARG 抗体
- PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
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抗原表位
- AA 25-5, Isoform 1
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PPARG antibody is un-conjugated
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应用范围
- ELISA
- 产品特性
- Concentration Definition: by UV absorbance at 280 nm
- 免疫原
- This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 255 -268 of human PPAR gamma .
- 亚型
- IgG
- Top Product
- Discover our top product PPARG Primary Antibody
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- 应用备注
- This affinity-purified antibody has been tested for use in ELISA. Specific conditions for reactivity should be optimized by the end user.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.0 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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MicroRNA regulation of adipose derived stem cells in aging rats." in: PLoS ONE, Vol. 8, Issue 3, pp. e59238, (2013) (PubMed).
: "A novel pregnane X receptor and S14-mediated lipogenic pathway in human hepatocyte." in: Hepatology (Baltimore, Md.), Vol. 49, Issue 6, pp. 2068-79, (2009) (PubMed).
: "Evidence for multiple peroxisome proliferator-activated receptor gamma transcripts in bone: fine-tuning by hormonal regulation and mRNA stability." in: FEBS letters, Vol. 582, Issue 11, pp. 1618-24, (2008) (PubMed).
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MicroRNA regulation of adipose derived stem cells in aging rats." in: PLoS ONE, Vol. 8, Issue 3, pp. e59238, (2013) (PubMed).
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- 抗原
- PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
- 别名
- PPAR gamma 1 + 2 (PPARG 产品)
- 别名
- PPAR gamma antibody, PPARg2 antibody, PPARG antibody, Nr1c3 antibody, PPAR-gamma antibody, PPAR-gamma2 antibody, PPARgamma antibody, PPARgamma2 antibody, NR1C3 antibody, CIMT1 antibody, GLM1 antibody, PPARG1 antibody, PPARG2 antibody, xPPAR-gamma antibody, PPAR-GAMMA antibody, PPARGAMMA antibody, peroxisome proliferator-activated receptor gamma antibody, peroxisome proliferator activated receptor gamma antibody, peroxisome proliferator activated receptor gamma L homeolog antibody, PPARG antibody, Pparg antibody, pparg.L antibody
- 背景
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Since their discovery in the early 1990's, the peroxisome proliferator activated receptors (PPARs) have attracted significant attention. This is primarily because PPARs serve as receptors for two very important classes of drugs: the hypolipidemic fibrates and the insulin sensitizing thiazolidinediones. Peroxisome proliferators are non-genotoxic carcinogens that are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family termed PPARs. Nuclear hormone receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Upon binding fatty acids or hypolipidemic drugs, PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate the expression of target genes. There are 3 known subtypes of PPARs: PPAR-alpha, PPAR-delta and PPAR-gamma. Mostly target genes are involved in the catabolism of fatty acids. Conversely, PPAR-gamma is activated by peroxisome proliferators such as prostaglandins, leukotrienes and anti-diabetic thiazolidinediones and affects the expression of genes involved in the storage of the fatty acids. PPAR-gamma may also be involved in adipocyte differentiation. It has also been shown that PPARs can induce transcription of acyl coenzyme A oxidase and cytochrome P450 through interaction with specific response elements.
Synonyms: HUMPPARG antibody, NR1C3 antibody, PPAR gamma antibody, PPARG antibody, PPARG1 antibody, PPARG2 antibody - 基因ID
- 5468, 20336229
- UniProt
- P37231
- 途径
- MAPK Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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