ANAPC4 产品
(Anaphase Promoting Complex Subunit 4 (ANAPC4))
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A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. [provided by RefSeq, Jul 2008].
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Recommended ANAPC4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN526177
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
Cat. No.
ABIN6991324
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
Cat. No.
ABIN7510297
Quantity
50 μg
Datasheet
Datasheet
Recommended ANAPC4 蛋白
Latest Publications for our ANAPC4 Products
: "Hyperphosphorylation of CDH1 in Glioblastoma Cancer Stem Cells Attenuates APC/CCDH1 Activity and Pharmacologic Inhibition of APC/CCDH1/CDC20 Compromises Viability." in: Molecular cancer research : MCR, Vol. 17, Issue 7, pp. 1519-1530, (2019) (PubMed).: "Sphingosine kinase 1 is overexpressed and promotes proliferation in human thyroid cancer." in: Molecular endocrinology (Baltimore, Md.), Vol. 25, Issue 11, pp. 1858-66, (2011) (PubMed).
Synonyms and alternative names related to ANAPC4
anaphase promoting complex subunit 4 (Anapc4), anaphase promoting complex subunit 4 L homeolog (anapc4.L), anaphase promoting complex subunit 4 (ANAPC4), anaphase promoting complex subunit 4 (anapc4), Transducin/WD40 repeat-like superfamily protein (APC4), 2610306D21Rik, ANAPC4, APC4, D5Ertd249e, DDBDRAFT_0186409, DDBDRAFT_0234268, DDB_0186409, DDB_0234268, F18E5.150, F18E5_150, MGC81278Protein level used designations for ANAPC4
- anaphase-promoting complex subunit 4
- anaphase promoting complex subunit 4
- Cyclosome subunit 4
- cyclosome subunit 4
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