ANAPC4 抗体
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北京 101111
Quick Overview for ANAPC4 抗体 (ABIN7227326)
抗原
See all ANAPC4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-APC4 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of APC4 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human APC4 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- ANAPC4 (Anaphase Promoting Complex Subunit 4 (ANAPC4))
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别名
- APC4
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背景
- Anaphase-promoting complex subunit 4(APC4), Cyclosome subunit 4A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. Two transcript variants encoding different isoforms have been found for this gene. APC4 (Anaphase Promoting Complex Subunit 4) is a Protein Coding gene. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Cell Cycle, Mitotic.
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分子量
- 88kD
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基因ID
- 29945
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UniProt
- Q9UJX5
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途径
- M Phase
抗原
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