anti-Histidine Triad Nucleotide Binding Protein 1 (HINT1) 抗体

The protein encoded by HINT1 can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. 再加上,我们可以发HINT1 蛋白 (14)HINT1 试剂盒 (6)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
HINT1 3094 P49773
HINT1 15254 P70349
HINT1 690660 P62959
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antibodies-online.cn销售最多的anti-HINT1 抗体

Showing 10 out of 75 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 IHC, WB 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 IHC, WB Host: Rabbit <br /> Target Name: HINT1 <br /> Sample Tissue: Human Jurkat <br /> Antibody Dilution: 1.0 µg/mL HINT1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 IHC (p), WB Anti- HINT1 Picoband antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue Anti- HINT1 Picoband antibody, IHC(P) IHC(P): Mouse Intestine Tissue 100 μg Log in to see 4至6个工作日
$280.00
详细
非结合性 IF, ELISA, WB Western blot analysis of extracts from Jurkat cells, using HINT1 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HeLa cells, using HINT1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
小鸡 非结合性 IHC, IHC (p), WB Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-HINT1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml. This image was taken for the unconjugated form of this product. Other f ... 50 μg Log in to see 11至14个工作日
$727.83
详细
小鸡 非结合性 IHC, IHC (p), WB Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-HINT1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml. This image was taken for the unconjugated form of this product. Other f ... 50 μg Log in to see 11至14个工作日
$727.83
详细
非结合性 ELISA, ICC, IF, WB Western blot analysis of extracts from Jurkat cells, using HINT1 antibody. ABIN6274268 staining Hela cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibody. 100 μL Log in to see 11至12个工作日
$390.77
详细
非结合性 WB Western blot analysis of extract of various cells, using HINT1 antibody. 100 μL Log in to see 16 Days
$334.77
详细
非结合性 IHC, IHC (p), WB Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-HINT1 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Log in to see 11至14个工作日
$484.00
详细
小鼠 非结合性 IF, IHC (p), ELISA, WB Western Blot analysis of HINT1 expression in transfected 293T cell line by HINT1 monoclonal antibody (M05), clone 2D7.Lane 1: HINT1 transfected lysate(13.8 KDa).Lane 2: Non-transfected lysate. Immunoperoxidase of monoclonal antibody to HINT1 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml] 100 μg Log in to see 11至12个工作日
$354.20
详细

引用最多的anti-HINT1 抗体

  1. Human Polyclonal HINT1 Primary Antibody for ELISA, WB - ABIN516451 : Rodríguez-Muñoz, Sánchez-Blázquez, Vicente-Sánchez, Bailón, Martín-Aznar, Garzón: The histidine triad nucleotide-binding protein 1 supports mu-opioid receptor-glutamate NMDA receptor cross-regulation. in Cellular and molecular life sciences : CMLS 2011 (PubMed)
    Show all 2 Pubmed References

更多抗HINT1的相互作用对抗体

Human Histidine Triad Nucleotide Binding Protein 1 (HINT1) interaction partners

  1. Hint1 has been shown to be essential for the metabolic activation of nucleotide antiviral pronucleotides (i.e., proTides). These results provide mechanistic insights underpinning histidine nucleophilic catalysis in general and human Hint1 catalysis, in particular, thus aiding the design of future proTides and the elucidation of the natural function of the Hint family of enzymes.

  2. We provide a comprehensive overview of the structural and functional characteristics of the HINT1 protein that may guide further studies into the molecular aetiology and treatment strategies--{REVIEW}

  3. Underexpression of Hint1 is associated with invasion of hepatocellular carcinoma.

  4. first structure (at a 2.34A resolution) of a complex of human HINT1 with a non-hydrolyzable analog of an Ap4A dinucleotide

  5. Absence of HINT1 mutations in a UK and Spanish cohort of patients with inherited neuropathies

  6. In hepatocellular carcinoma, HINT1 is a regulator of IkappaBalpha (显示 NFKBIA 抗体) through SCF (显示 KITLG 抗体)(beta-TrCP (显示 BTRC 抗体)) E3 ligase.

  7. HINT1 mutations seem to be one of the most frequent causes of inherited neuropathy and are probably the most frequent cause of HMN in Czech patients. We suggest all HMN/CMT2 patients be tested for the presence of the prevalent mutation, the p.R37P

  8. The teneurin-1 intracellular domain binds HINT1, thus switching on MITF-dependent transcription of GPNMB.

  9. Data suggest that histidine triad nucleotide binding protein 1 (HINT1) should be added to the list of genes to check for in distal hereditary motor neuropathies (dHMNs).

  10. Study gives suggestive evidence that HINT1 rs3852209 may be related to smoking status in Chinese men.

Mouse (Murine) Histidine Triad Nucleotide Binding Protein 1 (HINT1) interaction partners

  1. Increased PKC activity and altered GSK3B/NMDAR (显示 GRIN1 抗体) function drive behavior cycling in HINT1-deficient mice.

  2. Study shows that social isolation to a series of schizophrenia-related deficits and that potential interactions among histidine triad nucleotide binding protein 1, NMDA receptor 1 (显示 GRIN1 抗体), and dopamine receptor 2 (显示 DRD2 抗体) may underlie the behavioral deficits induced by social isolation.

  3. The absence of Hint1 gene enhances supraspinal nociceptive sensitivity in mice, including thermal, mechanical and inflammatory hyperalgesia.

  4. It was observed that HINT1 protein binds to GPCRs and NMDAR NR1 (显示 GRIN1 抗体) subunits in a calcium-independent manner, whereas sigma1R (显示 SIGMAR1 抗体) binding to these proteins increases in the presence of calcium.

  5. Results suggest that Hint1 deficiency leads to an increased protein level of PKC gamma (显示 PRKCG 抗体) in the brain and a compromised activation response of PKC gamma (显示 PRKCG 抗体) upon stimulation

  6. HINT1 is involved in the behavioral abnormalities induced by social isolation and exerts distinct roles in different encephalic regions.

  7. These results further support a role for HINT1 in nicotine-mediated behaviors and suggest that alterations in the gene may have differential effects on phenotype in males and females.

  8. Activated mu-opioid receptors stimulate the production of nitric oxide (NO), and the redox zinc switch RGSZ2 (显示 RGS17 抗体) converts this signal into free zinc ions that are required to recruit the redox sensor PKCgamma (显示 PRKCG 抗体) to HINT1 proteins.

  9. lipidomic phenotype of the Hint1(-/-) mouse

  10. these mice do not provide a disease model or a means for investigating the basis of HINT1-associated neuropathy and neuromyotonia

Rabbit Histidine Triad Nucleotide Binding Protein 1 (HINT1) interaction partners

  1. structure of the rabbit HINT1-adenosine complex is reported at 1.10 A resolution, which is one of the highest resolutions obtained for a HINT1 structure

HINT1 抗原简介

蛋白简介

The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. This gene has been found to be a tumor suppressing gene. Several transcript variants, but only one of them protein-coding, have been found for this gene.

Gene names and symbols associated with HINT1

  • histidine triad nucleotide binding protein 1 (HINT1) 抗体
  • histidine triad nucleotide binding protein 1 (hint1) 抗体
  • histidine triad nucleotide binding protein 1 (Hint1) 抗体
  • histidine triad nucleotide binding protein 1 S homeolog (hint1.S) 抗体
  • histidine triad nucleotide binding protein 1-Z (HINT1Z) 抗体
  • Histidine triad nucleotide-binding protein 1 (hint-1) 抗体
  • AA673479 抗体
  • CHPKCI 抗体
  • Hint 抗体
  • HINTZ 抗体
  • Ipk1 抗体
  • NMAN 抗体
  • Pkci 抗体
  • PKCI-1 抗体
  • PKCIZ 抗体
  • Prkci 抗体
  • PRKCNH1 抗体
  • zgc:103764 抗体

Protein level used designations for HINT1

histidine triad nucleotide binding protein 1 , PKCI-Z-related protein , adenosine 5'-monophosphoramidase , histidine triad nucleotide-binding protein 1 , protein kinase C inhibitor 1 , protein kinase C-interacting protein 1 , PKC inhibitor/ interacting protein , 17 kDa inhibitor of protein kinase C , PKCI-1 , protein kinase C, iota , histidine triad missing Z , protein kinase C inhibitor , P13.7

GENE ID SPECIES
462040 Pan troglodytes
548919 Xenopus (Silurana) tropicalis
751976 Taeniopygia guttata
3094 Homo sapiens
15254 Mus musculus
690660 Rattus norvegicus
449551 Danio rerio
447082 Xenopus laevis
395424 Gallus gallus
327693 Bos taurus
100009302 Oryctolagus cuniculus
474667 Canis lupus familiaris
100171549 Pongo abelii
184760 Caenorhabditis elegans
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