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EXOSC2 抗体

(Exosome Component 2 (EXOSC2))
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC2 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits through contacts with EXOSC4 and EXOSC7.
EXOSC2 抗体  (AA 1-293) EXOSC2 抗体  (AA 1-293) EXOSC2 抗体 (AA 1-293) (ABIN7441514)

EXOSC2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

EXOSC2 抗体  (AA 1-293) EXOSC2 抗体  (AA 1-293) EXOSC2 抗体 (AA 1-293) (ABIN6140374)

EXOSC2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

EXOSC2 抗体  (AA 71-160) EXOSC2 抗体  (AA 71-160) EXOSC2 抗体 (AA 71-160) (ABIN565068)

EXOSC2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

EXOSC2 抗体 by 适用

Find EXOSC2 抗体 for a variety of species such as anti-Human EXOSC2, anti-Mouse EXOSC2, anti-Dog EXOSC2. The species listed below are among those available. Click on a link to go to the corresponding products.

EXOSC2 抗体 by 应用范围

Find EXOSC2 抗体 validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

EXOSC2 抗体 by 抗体来源

Find EXOSC2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

EXOSC2 抗体 by 抗原表位

Find EXOSC2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

EXOSC2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal EXOSC2 抗体. Click on a link to go to the corresponding products.

EXOSC2 抗体 by 克隆

Find EXOSC2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

Popular EXOSC2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (9)
Cat. No. ABIN7441514
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN6140374
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN565068
Quantity 50 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN2779057
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
  • (1)
Cat. No. ABIN525144
Quantity 100 μg
Datasheet Datasheet
Reactivity Dog, Guinea Pig, Human, Monkey, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN202179
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Chicken, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit
Application WB
Validations
  • (1)
Cat. No. ABIN6740694
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
  • (1)
Cat. No. ABIN1881328
Quantity 400 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN2779056
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF
Validations
Cat. No. ABIN7114010
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
Cat. No. ABIN7114011
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, ICC, IHC (p)
Validations
Cat. No. ABIN7465776
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IP
Validations
Cat. No. ABIN7449729
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
Cat. No. ABIN7133432
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN2600842
Quantity 400 μL
Datasheet Datasheet

Latest Publications for our EXOSC2 抗体

van Dijk, Schilders, Pruijn: "Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways." in: RNA (New York, N.Y.), Vol. 13, Issue 7, pp. 1027-35, (2007) (PubMed).

Humphray, Oliver, Hunt, Plumb, Loveland, Howe, Andrews, Searle, Hunt, Scott, Jones, Ainscough, Almeida, Ambrose, Ashwell, Babbage, Babbage, Bagguley, Bailey, Banerjee, Barker, Barlow, Bates, Beasley et al.: "DNA sequence and analysis of human chromosome 9. ..." in: Nature, Vol. 429, Issue 6990, pp. 369-74, (2004) (PubMed).

Mitchell, Petfalski, Shevchenko, Mann, Tollervey: "The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases." in: Cell, Vol. 91, Issue 4, pp. 457-66, (1997) (PubMed).

Aliases for EXOSC2 抗体

exosome component 2 (EXOSC2) 抗体
exosome component 2 (exosc2) 抗体
exosome component 2 (Bm1_33895) 抗体
exosome component 2 (PTRG_00114) 抗体
exosome component 2 (Exosc2) 抗体
exosome component 2 L homeolog (exosc2.L) 抗体
EXOSC2 抗体
exosc2 抗体
fa97b01 抗体
hRrp4p 抗体
MGC97533 抗体
p7 抗体
RRP4 抗体
Rrp4 抗体
Rrp4p 抗体
wu:fa97b01 抗体
zgc:110117 抗体
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