EXOSC7 抗体
(Exosome Component 7 (EXOSC7))
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.
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53 results
EXOSC7
适用: 人, 大鼠, 小鼠, 犬, Cow, 马, 豚鼠, 兔, 斑马鱼, 猴
WB, IHC, IHC (p)
宿主: 兔
Polyclonal
unconjugated
2 images
EXOSC7
适用: 人, 大鼠, 小鼠, 犬, Cow, 马, Pig, Bat
WB
宿主: 兔
Polyclonal
unconjugated
1 image
EXOSC7
适用: 人, 大鼠
IF (p), IF (cc)
宿主: 兔
Polyclonal
AbBy Fluor® 750
EXOSC7
适用: 人, 大鼠
IF (p), IF (cc)
宿主: 兔
Polyclonal
AbBy Fluor® 680
EXOSC7
适用: 人, 大鼠
IF (p), IF (cc)
宿主: 兔
Polyclonal
AbBy Fluor® 488
EXOSC7
适用: 人, 大鼠
IF (p), IF (cc)
宿主: 兔
Polyclonal
AbBy Fluor® 555
EXOSC7
适用: 人, 大鼠
IF (p), IF (cc)
宿主: 兔
Polyclonal
AbBy Fluor® 350
EXOSC7
适用: 人, 大鼠
IF (p), IF (cc)
宿主: 兔
Polyclonal
AbBy Fluor® 647
Aliases for EXOSC7 抗体
exosome component 7 (exosc7) 抗体exosome component 7 (EXOSC7) 抗体
exosome component 7 S homeolog (exosc7.S) 抗体
exosome component 7 (Exosc7) 抗体
2610002K22Rik 抗体
AV212732 抗体
EAP1 抗体
EXOSC7 抗体
hRrp42p 抗体
mKIAA0116 抗体
p8 抗体
RRP42 抗体
Rrp42p 抗体
zgc:110717 抗体
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