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EXOSC7 产品

(Exosome Component 7 (EXOSC7))

Categories

Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.

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Featured EXOSC7 Categories

EXOSC7 抗体

High quality antibodies with extensive validation data.

EXOSC7 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

EXOSC7 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended EXOSC7 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Dog, Human, Monkey, Mouse, Rat
Application WB, IHC, IF, IHC (p), FACS
Validations
  • (14)
Cat. No. ABIN1498140
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN524917
Quantity 50 μg
Datasheet Datasheet

Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN202173
Quantity 100 μL
Datasheet Datasheet

Recommended EXOSC7 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955672
Quantity 96 tests
Datasheet Datasheet

Recommended EXOSC7 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122864
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353250
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353252
Quantity 10 μg
Datasheet Datasheet

Synonyms and alternative names related to EXOSC7

exosome component 7 (exosc7), exosome component 7 (EXOSC7), exosome component 7 S homeolog (exosc7.S), exosome component 7 (Exosc7), 2610002K22Rik, AV212732, EAP1, EXOSC7, hRrp42p, mKIAA0116, p8, RRP42, Rrp42p, zgc:110717

Protein level used designations for EXOSC7

  • exosome component 7
  • exosome complex component RRP42
  • exosome complex exonuclease RRP42
  • ribosomal RNA-processing protein 42
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