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Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. 再加上，我们可以发CXCL11 抗体 (175) 和 CXCL11 试剂盒 (71)和数多这个蛋白质的别的产品。
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cloning and characterization of expressed gene sequences of the interferon-gamma (显示 IFNG 蛋白) inducible chemokine (显示 CCL1 蛋白) CXCL11, or I-TAC, associated with type 1 T-helper immune responses
Neuroendocrine-like cells promote the chemotaxis activity of tumor-associated macrophages (TAM (显示 CCNA1 蛋白)) via CXCL10 (显示 CXCL10 蛋白) and CXCL11.
High CXCL11 expression is associated with clear-cell renal cell carcinoma (显示 MOK 蛋白).
CCL5 (显示 CCL5 蛋白) and CXCL11 expression were also induced in response to the activation of the PKC (显示 PRRT2 蛋白) pathway, and gene silencing experiments indicated that their inducible expression was dependent on RIPK4 (显示 RIPK4 蛋白) and IRF6 (显示 IRF6 蛋白). Moreover, gene reporter assays suggested that RIPK4 (显示 RIPK4 蛋白) induces CCL5 (显示 CCL5 蛋白) and CXCL11 expression by stimulating the transactivation of their promoters by IRF6 (显示 IRF6 蛋白).
data suggest that STAT2 (显示 STAT2 蛋白) plays a role in the psoriasis pathogenesis by regulating the expression of CXCL11 and CCL5 (显示 CCL5 蛋白), and thereby attracting IFNgamma-producing immune cells to the skin
this study shows that melanoma peptides vaccination and intratumoral administration of IFNgamma increases production of CXCL11 in patient tumors
S100A9 (显示 S100A9 蛋白) and S100A12 (显示 S100A12 蛋白) may have a role in the pathogenesis of pneumonia: S100A9 (显示 S100A9 蛋白) and CXCL1 (显示 CXCL1 蛋白) may contribute solely in mild pneumonia, and CCL5 (显示 CCL5 蛋白) and CXCL11 may contribute in severe pneumonia.
Downregulation of CXC chemokine (显示 CXCL12 蛋白) ligand 11 can inhibit tumor angiogenesis, suggesting that anti-CXC chemokine (显示 CXCL12 蛋白) ligand 11 therapy may offer an alternative treatment strategy for TWIST1 (显示 TWIST1 蛋白)-positive ovarian cancer
CXCL8 (显示 IL8 蛋白)/11 may promote the disease progression of osteoarthritis (OA), and may also serve as new therapeutic targets for treatment of OA.
this study shows that oxidative signaling inhibits T lymphocyte chemotaxis to the inflammatory chemokine (显示 CCL1 蛋白) CXCL11
The homozygous variant CXCL11 AA genotype (rs6817952) is associated with an increased risk of contact allergy.
These findings functionally integrate K17 (显示 KRT17 蛋白), hnRNP K (显示 HNRNPK 蛋白), and gene expression along with RSK (显示 RPS6KA1 蛋白) and CXCR3 (显示 CXCR3 蛋白) signaling in a keratinocyte-autonomous axis and provide a potential basis for their implication in tumorigenesis
very low doses of CXCL11 rapidly suppress signs of EAE in C57BL/6 mice lacking functional CXCL11.
Data indicate that epidermis-derived I-TAC (Cxcl11) triggers a sustained Th2-response that determines the outcome of a complex immunological process.
Analysis of genes within the Listr1 locus identified a frameshift mutation in the Cxcl11 gene of the C57BL/6 strain that prevents production of the mature chemokine (显示 CCL1 蛋白) CXCL11.
Cxcl10 (显示 CXCL10 蛋白) and cxcl11 are new hair-specific transcriptional targets of ectodysplasin, and they indicates involvement of chemokines in hair development.
the CXCL11-heparin interaction has two different affinities for glycosaminoglycans
I-TAC can have an important role during virus infections and vaccinia virus has evolved ways to avoid inducing I-TAC expression.
I-TAC acts as an antagonist for CCR5. I-TAC inhibited the binding of macrophage-inflammatory protein-1alpha (MIP-1alpha (显示 CCL3 蛋白))/CC chemokine ligand 3 (CCL3 (显示 CCL3 蛋白)) to cells transfected with CCR5 and to monocytes.
CXCL11 gene induction by interferon (显示 IFNA 蛋白) is STAT3 (显示 STAT3 蛋白) dependent
Acute ethanol intoxication impairs lung expression of Cxcl11, interfering with pulmonary response to bacterial challenge.
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene.
C-X-C motif chemokine 11
, Small-inducible cytokine B11
, interferon-inducible T-cell alpha chemoattractant CXCL11
, chemokine C-X-C motif ligand 11
, small inducible cytokine B11
, interferon gamma-inducible protein 9
, interferon-inducible T-cell alpha chemoattractant
, small inducible cytokine subfamily B (Cys-X-Cys), member 11
, small inducible cytokine subfamily B (Cys-X-Cys), member 9B
, small-inducible cytokine B11