Cullin 2 蛋白
(Cullin 2 (CUL2))
Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. May serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF).
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| Cullin 2 Protein (CUL2) (AA 1-745) (His tag) | 小鼠 | HEK-293 Cells |
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| Cullin 2 Protein (CUL2) (AA 1-745) (His tag) | 人 | HEK-293 Cells |
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| Cullin 2 Protein (CUL2) (AA 1-745) (GST tag) | 人 | 小麦胚 |
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| Cullin 2 Protein (CUL2) (AA 1-100) (GST tag) | 人 | 小麦胚 |
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| Cullin 2 Protein (CUL2) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| Cullin 2 Protein (CUL2) (AA 1-745) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| Cullin 2 Protein (CUL2) (AA 1-745) (Strep Tag) | 小鼠 | Cell-free protein synthesis (CFPS) |
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| Cullin 2 Protein (CUL2) (AA 511-745) (His tag,GST tag) | 人 | 大肠杆菌（E. Coli） |
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| Cullin 2 Protein (CUL2) (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| Cullin 2 Protein (CUL2) (AA 526-745) (His tag) | 人 | Bacteria |
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| Cullin 2 Protein (CUL2) (His tag) | 人 | 大肠杆菌（E. Coli） |
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Protein
- PS (Protein Structure: 有验证图片)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Protein
- PS (Protein Structure: 有验证图片)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Aliases for Cullin 2 蛋白
cullin 2 (cul2) 蛋白cullin 2 (CUL2) 蛋白
cullin-2 (PTRG_05231) 蛋白
putative cullin-2 (cul-2) (Smp_079740) 蛋白
cullin-2 (LOC100550749) 蛋白
cullin 2 (Cul2) 蛋白
cullin 2 L homeolog (cul2.L) 蛋白
Cullin-2 (cul-2) 蛋白
1300003D18Rik 蛋白
4932411N15Rik 蛋白
AI327301 蛋白
ATCUL2 蛋白
cul2 蛋白
Cullin-2 蛋白
cullin-2 蛋白
cullin 2 蛋白
F22D16.2 蛋白
F22D16_2 蛋白
fj48a06 蛋白
LOC100221330 蛋白
mKIAA4106 蛋白
wu:fj48a06 蛋白
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