CXCR2 蛋白
(Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| CXCR2 Protein (DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| CXCR2 Protein (AA 1-48) (Fc Tag) | 人 | HEK-293 Cells |
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| CXCR2 蛋白 | 人 | 小麦胚 |
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| CXCR2 Protein (AA 1-360) (GST tag) | 人 | 小麦胚 |
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| CXCR2 Protein (GST tag) | 人 | 大肠杆菌（E. Coli） |
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| CXCR2 Protein (AA 1-360) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| CXCR2 Protein (AA 1-359) (Strep Tag) | 小鼠 | Cell-free protein synthesis (CFPS) |
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| CXCR2 Protein (DYKDDDDK Tag,Strep Tag) | 人 | HEK-293 Cells |
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| CXCR2 Protein (AA 1-45) (Fc Tag) | 小鼠 | HEK-293 Cells |
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| CXCR2 Protein (AA 1-63) (Fc Tag) | Cynomolgus | HEK-293 Cells |
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| CXCR2 Protein-VLP (AA 1-360, full length) (His tag) | 人 | Mammalian Cells |
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| CXCR2 Protein (AA 1-57) (His tag,GST tag) | 人 | 大肠杆菌（E. Coli） |
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| CXCR2 蛋白 | 小鼠 | 合成 |
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| CXCR2 Protein (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| CXCR2 Protein (partial) (His-SUMO Tag) | 人 | 大肠杆菌（E. Coli） |
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| CXCR2 Protein (AA 1-57) (GST tag) | 人 | Bacteria |
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| CXCR2 蛋白 | 小鼠 | 大肠杆菌（E. Coli） |
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| CXCR2 Protein (AA 1-63, AA 99-330) (hFc Tag) | Cynomolgus | HEK-293 Cells |
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| CXCR2 Protein (AA 1-45, AA 99-330) (hFc Tag) | 小鼠 | HEK-293 Cells |
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| CXCR2 Protein (AA 1-63, AA 99-330) (hFc Tag) | Cynomolgus | HEK-293 Cells |
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Protein
- ELISA (ELISA: 有验证图片)
- SDS (SDS-PAGE: 有验证图片)
- Imm (Immunogen: 所列应用)
- cryo-EM (Cryogenic electron microscopy: 所列应用)
- PhD (Phage Display: 所列应用)
- SPR (Surface Plasmon Resonance: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Synthetic Nanodisc
Protein
- SDS (SDS-PAGE: 有验证图片)
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
1 reference
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- Imm (Immunogen: 所列应用)
- ELISA (ELISA: 所列应用)
- cryo-EM (Cryogenic electron microscopy: 所列应用)
- PhD (Phage Display: 所列应用)
- SPR (Surface Plasmon Resonance: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Synthetic Nanodisc
Protein
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- Cynomolgus
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- 宿主
- 人
- 宿主
- Mammalian Cells
- 蛋白类型
- VLP
- 纯度
- The purity information is not available for VLPs proteins.
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 80 %
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- 宿主
- Cynomolgus
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- 宿主
- Cynomolgus
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Latest Publications for our CXCR2 蛋白
: "Direct Macromolecular Drug Delivery to Cerebral Ischemia Area using Neutrophil-Mediated Nanoparticles." in: Theranostics, Vol. 7, Issue 13, pp. 3260-3275, (2018) (PubMed).
: "The staphylococcal toxins ?-haemolysin AB and CB differentially target phagocytes by employing specific chemokine receptors." in: Nature communications, Vol. 5, pp. 5438, (2014) (PubMed).
: "The staphylococcal toxins ?-haemolysin AB and CB differentially target phagocytes by employing specific chemokine receptors." in: Nature communications, Vol. 5, pp. 5438, (2014) (PubMed).
Aliases for CXCR2 蛋白
C-X-C motif chemokine receptor 2 (Cxcr2) 蛋白C-X-C motif chemokine receptor 2 (CXCR2) 蛋白
chemokine (C-X-C motif) receptor 2 (Cxcr2) 蛋白
CD128 蛋白
CD182 蛋白
CDw128 蛋白
CDw128b 蛋白
CMKAR2 蛋白
Cmkar2 蛋白
CXC-R2 蛋白
CXCR-2 蛋白
Gpcr16 蛋白
IL-8rb 蛋白
IL-8Rh 蛋白
IL8R2 蛋白
IL8RA 蛋白
IL8RB 蛋白
Il8rb 蛋白
mIL-8RH 蛋白
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