anti-小鼠 MET 抗体 for Immunofluorescence (Paraffin-embedded Sections)

Recommended MET Antibody (supplied by: Log in to see )

抗原
Met Proto-Oncogene (MET) 抗体
  • AUTS9
  • HGFR
  • RCCP2
  • c-Met
  • AI838057
  • HGF
  • Par4
  • Hgfr
  • c-met
  • MET proto-oncogene, receptor tyrosine kinase
  • met proto-oncogene
  • MET
  • Met
抗原表位
AA 1345-1385, pTyr1365
82
78
61
47
41
30
23
19
16
15
15
15
14
14
7
6
6
6
5
5
5
4
4
4
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
适用
人, 小鼠, 大鼠
706
280
213
19
15
8
6
6
5
3
3
3
3
2
1
1
1
1
宿主

443
268
5
5
4
克隆类型
多克隆
标记
This MET antibody is un-conjugated
24
24
23
19
19
13
12
10
8
7
7
7
7
7
6
6
6
6
6
6
6
5
5
5
5
5
5
4
1
1
应用范围
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
494
199
133
129
109
79
64
36
24
19
13
10
8
6
3
2
1
1
1
1
1
1
选项
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产品编号 ABIN733658
$ 340.45
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN671661 FACS IF (p) IHC (p) WB Rabbit IgG AA 25-75 Log in to see Polyclonal 3
1 ABIN743843 IF (p) IHC (p) WB Rabbit IgG pTyr1234, pTyr1235, AA 1220-1240 Log in to see Polyclonal
1 ABIN2810532 IF (p) Alexa Fluor 594 Rabbit IgG AA 1220-1240, pTyr1234, pTyr1235 Log in to see Polyclonal
1 ABIN2177593 IF (p) IHC (p) WB Rabbit IgG pTyr1003 Log in to see Polyclonal
1 ABIN743846 IF (p) Cy3 Rabbit IgG pTyr1234, pTyr1235, AA 1220-1240 Log in to see Polyclonal
1 ABIN743847 IF (p) Cy5 Rabbit IgG pTyr1234, pTyr1235, AA 1220-1240 Log in to see Polyclonal
1 ABIN743848 IF (p) Cy5.5 Rabbit IgG pTyr1234, pTyr1235, AA 1220-1240 Log in to see Polyclonal
1 ABIN743850 IF (p) FITC Rabbit IgG pTyr1234, pTyr1235, AA 1220-1240 Log in to see Polyclonal
1 ABIN743849 IF (p) Cy7 Rabbit IgG pTyr1234, pTyr1235, AA 1220-1240 Log in to see Polyclonal
1 ABIN878860 IF (p) Alexa Fluor 555 Rabbit IgG pTyr1234, pTyr1235, AA 1220-1240 Log in to see Polyclonal
1 ABIN878859 IF (p) Alexa Fluor 488 Rabbit IgG pTyr1234, pTyr1235, AA 1220-1240 Log in to see Polyclonal
1 ABIN878858 IF (p) Alexa Fluor 350 Rabbit IgG pTyr1234, pTyr1235, AA 1220-1240 Log in to see Polyclonal
1 ABIN878861 IF (p) Alexa Fluor 647 Rabbit IgG pTyr1234, pTyr1235, AA 1220-1240 Log in to see Polyclonal
1 ABIN2808804 FACS IF (p) Alexa Fluor 594 Rabbit IgG AA 25-75 Log in to see Polyclonal
1 ABIN2810531 IF (p) Alexa Fluor 594 Rabbit IgG AA 1345-1385, pTyr1365 Log in to see Polyclonal
1 ABIN878981 IF (p) Alexa Fluor 647 Rabbit IgG AA 1345-1385, pTyr1365 Log in to see Polyclonal
1 ABIN878985 IF (p) Alexa Fluor 350 Rabbit IgG AA 1345-1385, pTyr1365 Log in to see Polyclonal
1 ABIN733663 IF (p) Cy5.5 Rabbit IgG AA 1345-1385, pTyr1365 Log in to see Polyclonal
1 ABIN733661 IF (p) Cy3 Rabbit IgG AA 1345-1385, pTyr1365 Log in to see Polyclonal
1 ABIN733662 IF (p) Cy5 Rabbit IgG AA 1345-1385, pTyr1365 Log in to see Polyclonal

General

抗原 Met Proto-Oncogene (MET) 抗体
抗原表位 AA 1345-1385, pTyr1365
(82), (78), (61), (47), (41), (30), (23), (19), (16), (15), (15), (15), (14), (14), (7), (6), (6), (6), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
适用 人, 小鼠, 大鼠
(706), (280), (213), (19), (15), (8), (6), (6), (5), (3), (3), (3), (3), (2), (1), (1), (1), (1)
宿主
(443), (268), (5), (5), (4)
克隆类型
多克隆
标记 This MET antibody is un-conjugated
(24), (24), (23), (19), (19), (13), (12), (10), (8), (7), (7), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (5), (5), (5), (5), (5), (5), (4), (1), (1)
应用范围 Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(494), (199), (133), (129), (109), (79), (64), (36), (24), (19), (13), (10), (8), (6), (3), (2), (1), (1), (1), (1), (1), (1)
Pubmed 找到1个引用
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MET抗体详情

MET目标详情 使用细节 贮存及处理 References for anti-MET antibody (ABIN733658) 图像
纯化方法 Purified by Protein A.
免疫原 KLH conjugated synthetic phosphopeptide derived from human C-Met around the phosphorylation site of Tyr1365
亚型 IgG

MET目标详情

MET抗体详情 使用细节 贮存及处理 References for anti-MET antibody (ABIN733658) 图像 回页首
抗原
别名 Phospho Met/C-Met (MET Antibody 摘要)
背景

Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects. During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation. In adults, participates in wound healing as well as organ regeneration and tissue remodeling. Promotes also differentiation and proliferation of hematopoietic cells. Acts as a receptor for Listeria internalin inlB, mediating entry of the pathogen into cells.

Subcellular location: Cytoplasm

Synonyms: HGFR, AUTS9, RCCP2, c-Met, Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met, MET

基因ID 4233
UniProt P08581
途径 RTK signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor

使用细节

MET抗体详情 MET目标详情 贮存及处理 References for anti-MET antibody (ABIN733658) 图像 回页首
应用备注 WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
限制 仅限研究用

贮存及处理

MET抗体详情 MET目标详情 使用细节 References for anti-MET antibody (ABIN733658) 图像 回页首
状态 Liquid
浓度 1 μg/μL
缓冲液 Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
储存条件 -20 °C
储存方法 Store at -20°C
有效期 12 months

References for anti-MET antibody (ABIN733658)

MET抗体详情 MET目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

Gao, Bing, Li, Yang, Li, Chen: "Study of critical role of c-Met and its inhibitor SU11274 in colorectal carcinoma." in: Medical oncology (Northwood, London, England), Vol. 30, Issue 2, pp. 546, 2013

图像

MET抗体详情 MET目标详情 使用细节 贮存及处理 References for anti-MET antibody (ABIN733658) 回页首
厂商提供的图像
Immunohistochemistry (IHC) image for anti-Met Proto-Oncogene (MET) (AA 1345-1385), (pTyr1365) antibody (ABIN733658) Formalin-fixed and paraffin embedded human stomach labeled with Anti-phospho C-Met/HG...
ELISA image for anti-Met Proto-Oncogene (MET) (AA 1345-1385), (pTyr1365) antibody (ABIN733658) anti-Met Proto-Oncogene (MET) (AA 1345-1385), (pTyr1365) antibody (Image 2)