anti-人 MET 抗体 for Immunohistochemistry (Frozen Sections)

Recommended MET Antibody (supplied by: Log in to see )

抗原
Met Proto-Oncogene (MET) 抗体
  • AUTS9
  • HGFR
  • RCCP2
  • c-Met
  • AI838057
  • HGF
  • Par4
  • Hgfr
  • c-met
  • MET proto-oncogene, receptor tyrosine kinase
  • met proto-oncogene
  • MET
  • Met
抗原表位
Cytoplasmic Domain
82
78
61
47
41
30
23
19
17
15
15
15
15
14
7
6
6
5
5
5
5
4
4
4
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
适用

706
281
214
19
15
8
6
6
5
3
3
3
3
2
1
1
1
1
宿主
小鼠
444
267
5
5
4
克隆类型
单克隆
标记
This MET antibody is un-conjugated
24
24
23
19
19
13
12
10
8
7
7
7
7
7
6
6
6
6
6
6
6
5
5
5
5
5
5
4
1
1
应用范围
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
495
199
133
129
109
79
65
36
24
19
13
10
7
6
3
2
1
1
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

产品编号 ABIN614469
$ 368.50
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN351534 IHC (fro) IHC (p) Mouse IgG2a Cytoplasmic Domain Log in to see
1 ABIN1724402 IHC (fro) IHC (p) Mouse IgG2a Cytoplasmic Domain Log in to see
1 ABIN1107526 EIA IHC (fro) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN2962074 IHC (fro) IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN5583438 IHC (fro) IHC (p) Mouse IgM Log in to see 8F11
1 ABIN2766341 IHC (fro) IHC (p) IHC Mouse IgG2a Cytoplasmic Domain Log in to see

General

抗原 Met Proto-Oncogene (MET) 抗体
抗原表位 Cytoplasmic Domain
(82), (78), (61), (47), (41), (30), (23), (19), (17), (15), (15), (15), (15), (14), (7), (6), (6), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
适用
(706), (281), (214), (19), (15), (8), (6), (6), (5), (3), (3), (3), (3), (2), (1), (1), (1), (1)
宿主 小鼠
(444), (267), (5), (5), (4)
克隆类型 (克隆位点)
单克隆   ( )
标记 This MET antibody is un-conjugated
(24), (24), (23), (19), (19), (13), (12), (10), (8), (7), (7), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (5), (5), (5), (5), (5), (5), (4), (1), (1)
应用范围 Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(495), (199), (133), (129), (109), (79), (65), (36), (24), (19), (13), (10), (7), (6), (3), (2), (1), (1), (1), (1), (1), (1)
Supplier Log in to see

MET抗体详情

MET目标详情 使用细节 贮存及处理 图像
特异性 Recognizes c-Met (Cytoplasmic Domain).
交叉反应 (详细) Species reactivity (tested):Human.
纯化方法 Purified
免疫原 Synthetic peptide derived from cytoplasmic domain of Human c-Met protein
克隆位点 IST-1
亚型 IgG2a

MET目标详情

MET抗体详情 使用细节 贮存及处理 图像 回页首
抗原
别名 HGF Receptor (MET Antibody 摘要)
背景 The c-Met protein is a receptor tyrosine kinase encoded by the c-Met proto-oncogene. c-Met, also known as HGF receptor or SF receptor, is activated by hepatocyte growth factor (HGF) or scatter factor (SF), and is composed of alpha and beta subunits linked by disulfide bonds. Dysregulated c-Met expression has been detected at both protein and mRNA levels in a variety of human carcinomas and sarcomas. Up to a 2.5-fold increase in mRNA expression has been reported in colorectal tumor tissues, and upregulation of the c-Met protein in association with increasingly malignant behavior has been described in prostate cancer, cutaneous malignant melanoma, and breast cancer. Recent studies using monoclonal Ms anti-c-Met (clone: 3D4) for immunohistochemistry in lymph node-negative breast carcinoma tissues demonstrated that high levels of c-Met expression are associated with poor patient clinical outcome, as assessed over 20-40 years of follow-up. Further, antibodies against the intracellular but not the extracellular domain of c-Met were prognostic, suggesting that overexpression of the cytoplasmic tail of c-Met may play an important role in breast cancer progression.Synonyms: HGF/SF receptor, Hepatocyte growth factor receptor, MET, Met proto-oncogene tyrosine kinase, Scatter factor receptor, c-Met
基因ID 4233
NCBI登录号 NP_000236
UniProt P08581
途径 RTK signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor

使用细节

MET抗体详情 MET目标详情 贮存及处理 图像 回页首
应用备注 Optimal working dilution should be determined by the investigator.
限制 仅限研究用

贮存及处理

MET抗体详情 MET目标详情 使用细节 图像 回页首
状态 Liquid
缓冲液 PBS, 7.4 containing 1 % BSA and 0.09 % Sodium Azide
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

图像

MET抗体详情 MET目标详情 使用细节 贮存及处理 回页首
厂商提供的图像
Immunohistochemistry (IHC) image for anti-Met Proto-Oncogene (MET) (Cytoplasmic Domain) antibody (ABIN614469) anti-Met Proto-Oncogene (MET) (Cytoplasmic Domain) antibody