|抗原||Brain-Specific Angiogenesis Inhibitor 1 (BAI1) 抗体|
|适用||人, 小鼠 其他选择|
|标记||This BAI1 antibody is un-conjugated 其他选择|
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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BAI1抗体详情BAI1目标详情 使用细节 贮存及处理 图像
|特异性||This antibody detects endogenous levels of BAI-1 protein.(region surrounding Gln732)|
|纯化方法||Affinity Chromatography using epitope-specific immunogen|
BAI1目标详情BAI1抗体详情 使用细节 贮存及处理 图像 回页首
|别名||BAI1 (BAI1 Antibody 摘要)|
|背景||Brain-specific angiogenesis inhibitors, including BAI-1, BAI-2 and BAI-3, are integral membrane proteins belonging to the G protein-coupled receptor 2 family. In addition to inhibiting angiogenesis in the brain, BAI proteins are also expressed in the heart, thymus, skeletal muscle, and a variety of cell lines. BAI-1 protein is specifically expressed in the brain and found to localize to the cytoplasm and membrane in neuronal cells of the cerebral cortex. Reduced expression of BAI-1 in some glioblastoma cell lines and cancer tissues implicates the functional role of BAI-1 as an inhibitor of angiogenesis. The exact mechanisms underlying BAI-1 anti-angiogenetic activity are still being investigated. BAI-1 may be involved in mediating the p53 signal in suppression of glioblastoma, as well as in cell adhesion and signal transduction. Additional research shows an inverse correlation with vascularization and BAI-1 expression in both colorectal carcinomas and pulmonary adenocarcinomas.Synonyms: BAI-1, Brain-specific angiogenesis inhibitor 1|
|分子量||approx. 174 kDa|
使用细节BAI1抗体详情 BAI1目标详情 贮存及处理 图像 回页首
ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
贮存及处理BAI1抗体详情 BAI1目标详情 使用细节 图像 回页首
|缓冲液||Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative|
|注意事项||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|注意事项||Avoid repeated freezing and thawing.|
|储存条件||4 °C/-20 °C|
|储存方法||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
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