BACE1 抗体
(Beta-secretase 1 (BACE1))
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| BACE1 抗体 (AA 112-324) | 人, 小鼠, 大鼠 | 小鼠 Monoclonal |
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| BACE1 抗体 (AA 22-501) | 人 | 小鼠 Monoclonal |
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| BACE1 抗体 (AA 401-501) | 人 | 兔 Polyclonal |
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| BACE1 抗体 (N-Term) | 人, 小鼠 | 兔 Polyclonal |
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| BACE1 抗体 (AA 22-322) | 人 | 兔 Polyclonal |
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| BACE1 抗体 (N-Term) | 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 | 兔 Polyclonal |
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| BACE1 抗体 (AA 72-121) | 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 猴, Pig, Bat, Hamster | 兔 Polyclonal |
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| BACE1 抗体 (C-Term) | 人, 猴 | 兔 Polyclonal |
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| BACE1 抗体 (C-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| BACE1 抗体 (AA 46-155) | 人 | 兔 Polyclonal |
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| Recombinant BACE1 抗体 | 人 | 兔 Monoclonal |
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| BACE1 抗体 (N-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| BACE1 抗体 (AA 476-501) | 人, 小鼠 | 兔 Polyclonal |
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| BACE1 抗体 (N-Term) | 人, 大鼠, 猴 | 兔 Polyclonal |
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| BACE1 抗体 | 人 | 兔 Monoclonal |
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| BACE1 抗体 (AA 170-428) | 人 | 兔 Polyclonal |
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| BACE1 抗体 (AA 1-476) | 人 | 兔 Polyclonal |
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| Recombinant BACE1 抗体 | 人 | Human Monoclonal |
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| BACE1 抗体 (AA 251-300) | 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, 猴, Pig, Bat, Hamster, 小鸡, 非洲爪蟾 | 兔 Polyclonal |
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| BACE1 抗体 (AA 190-430) | 小鼠 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 3C1C3
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 112-324
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 有验证图片)
- PLA (Proximity Ligation Assay: 有验证图片)
- ISt (Immunostaining: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 2C1
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 22-501
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- SDS (SDS-PAGE: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
5 references - 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 401-501
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB16874
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 38-70, N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 22-322
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (fp) (Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections): 有验证图片)
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 猴, Pig, Bat, Hamster
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 72-121
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF/ICC (Immunofluorescence (fixed cells): 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 46-155
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- 质量等级
- KD Validated
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 23GB4865
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB7137
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 476-501
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 大鼠, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 170-428
Primary Antibody
- WB (Western Blotting: 有验证图片)
- PLA (Proximity Ligation Assay: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-476
Primary Antibody
- SDS (SDS-PAGE: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- ELISA (ELISA: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- BLI (Bio-Layer Interferometry: 所列应用)
- Func (Functional Studies: 所列应用)
- SPR (Surface Plasmon Resonance: 所列应用)
- 适用
- 人
- 宿主
- Human
- 克隆形成能力
- Monoclonal
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG1
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 190-430
Latest Publications for our BACE1 抗体
: "Preclinical and randomized clinical evaluation of the p38α kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration." in: Nature communications, Vol. 13, Issue 1, pp. 5308, (2022) (PubMed).
: "Extracellular vesicles: where the amyloid precursor protein carboxyl-terminal fragments accumulate and amyloid-β oligomerizes." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 34, Issue 9, pp. 12922-12931, (2021) (PubMed).
: "A pleiotropic role for exosomes loaded with the amyloid β precursor protein carboxyl-terminal fragments in the brain of Down syndrome patients." in: Neurobiology of aging, Vol. 84, pp. 26-32, (2020) (PubMed).
: "NF-κB-regulated microRNA-574-5p underlies synaptic and cognitive impairment in response to atmospheric PM2.5 aspiration." in: Particle and fibre toxicology, Vol. 14, Issue 1, pp. 34, (2018) (PubMed).
: "An Anti-Parkinson's Disease Drug via Targeting Adenosine A2A Receptor Enhances Amyloid-β Generation and γ-Secretase Activity." in: PLoS ONE, Vol. 11, Issue 11, pp. e0166415, (2017) (PubMed).
: "Dopamine D2 receptor and β-arrestin 2 mediate Amyloid-β elevation induced by anti-parkinson's disease drugs, levodopa and piribedil, in neuronal cells." in: PLoS ONE, Vol. 12, Issue 3, pp. e0173240, (2017) (PubMed).
: "Effects of RAGE-Specific Inhibitor FPS-ZM1 on Amyloid-β Metabolism and AGEs-Induced Inflammation and Oxidative Stress in Rat Hippocampus." in: Neurochemical research, Vol. 41, Issue 5, pp. 1192-9, (2016) (PubMed).
: "NO2 inhalation promotes Alzheimer's disease-like progression: cyclooxygenase-2-derived prostaglandin E2 modulation and monoacylglycerol lipase inhibition-targeted medication." in: Scientific reports, Vol. 6, pp. 22429, (2016) (PubMed).
: "Osthole decreases beta amyloid levels through up-regulation of miR-107 in Alzheimer's disease." in: Neuropharmacology, Vol. 108, pp. 332-44, (2016) (PubMed).
: "Deficiency of Neuronal p38α MAPK Attenuates Amyloid Pathology in Alzheimer Disease Mouse and Cell Models through Facilitating Lysosomal Degradation of BACE1." in: The Journal of biological chemistry, Vol. 291, Issue 5, pp. 2067-79, (2016) (PubMed).
: "Extracellular vesicles: where the amyloid precursor protein carboxyl-terminal fragments accumulate and amyloid-β oligomerizes." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 34, Issue 9, pp. 12922-12931, (2021) (PubMed).
: "A pleiotropic role for exosomes loaded with the amyloid β precursor protein carboxyl-terminal fragments in the brain of Down syndrome patients." in: Neurobiology of aging, Vol. 84, pp. 26-32, (2020) (PubMed).
: "NF-κB-regulated microRNA-574-5p underlies synaptic and cognitive impairment in response to atmospheric PM2.5 aspiration." in: Particle and fibre toxicology, Vol. 14, Issue 1, pp. 34, (2018) (PubMed).
: "An Anti-Parkinson's Disease Drug via Targeting Adenosine A2A Receptor Enhances Amyloid-β Generation and γ-Secretase Activity." in: PLoS ONE, Vol. 11, Issue 11, pp. e0166415, (2017) (PubMed).
: "Dopamine D2 receptor and β-arrestin 2 mediate Amyloid-β elevation induced by anti-parkinson's disease drugs, levodopa and piribedil, in neuronal cells." in: PLoS ONE, Vol. 12, Issue 3, pp. e0173240, (2017) (PubMed).
: "Effects of RAGE-Specific Inhibitor FPS-ZM1 on Amyloid-β Metabolism and AGEs-Induced Inflammation and Oxidative Stress in Rat Hippocampus." in: Neurochemical research, Vol. 41, Issue 5, pp. 1192-9, (2016) (PubMed).
: "NO2 inhalation promotes Alzheimer's disease-like progression: cyclooxygenase-2-derived prostaglandin E2 modulation and monoacylglycerol lipase inhibition-targeted medication." in: Scientific reports, Vol. 6, pp. 22429, (2016) (PubMed).
: "Osthole decreases beta amyloid levels through up-regulation of miR-107 in Alzheimer's disease." in: Neuropharmacology, Vol. 108, pp. 332-44, (2016) (PubMed).
: "Deficiency of Neuronal p38α MAPK Attenuates Amyloid Pathology in Alzheimer Disease Mouse and Cell Models through Facilitating Lysosomal Degradation of BACE1." in: The Journal of biological chemistry, Vol. 291, Issue 5, pp. 2067-79, (2016) (PubMed).
Aliases for BACE1 抗体
beta-secretase 1 (BACE1) 抗体beta-site APP cleaving enzyme 1 (Bace1) 抗体
beta-secretase 1 (Bace1) 抗体
beta-site APP-cleaving enzyme 1 (bace1) 抗体
ASP2 抗体
BACE 抗体
Bace 抗体
BACE1 抗体
C76936 抗体
HSPC104 抗体
MGC145931 抗体
zgc:77409 抗体
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