anti-MAP2K7 (MAP2K7) 抗体产品概述

Full name:
anti-Mitogen-Activated Protein Kinase Kinase 7 抗体 (MAP2K7)
在www.antibodies-online.cn可供147 Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) 抗体的22不同的供货商。 再加上,我们可以发MAP2K7 试剂盒 (15)MAP2K7 蛋白 (13)和数多这个蛋白质的别的产品。 总共186 MAP2K7产品已列进来了。
别名:
2, 5930412N11Rik, JNKK, JNKK 2, Jnkk2, MAP2K7, map2k7-A, MAPKK7, MAPKK 7, Mek7, MEK 7, MKK7, Prkmk7, SAPKK-4, SAPKK4, sek2, si:ch211-254d18.2

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引用最多的anti-MAP2K7 抗体

  1. Human Monoclonal MAP2K7 Primary Antibody for ICC, FACS - ABIN969271 : Yoshizawa, Hammaker, Sweeney, Boyle, Firestein: Synoviocyte innate immune responses: I. Differential regulation of interferon responses and the JNK pathway by MAPK kinases. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
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  2. Cow (Bovine) Polyclonal MAP2K7 Primary Antibody for WB - ABIN2783609 : Tornatore, Marasco, Dathan, Vitale, Benedetti, Papa, Franzoso, Ruvo, Monti: Gadd45 beta forms a homodimeric complex that binds tightly to MKK7. in Journal of molecular biology 2008 (PubMed)

  3. Human Polyclonal MAP2K7 Primary Antibody for ELISA, WB - ABIN1450653 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)

更多抗MAP2K7的相互作用对抗体

Human Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) interaction partners

  1. MEK (显示 MAP2K1 抗体) activation cooperates with Cdkn2a (显示 CDKN2A 抗体) and Pten (显示 PTEN 抗体) inactivation to induce melanoma

  2. MKK7 undergoes neddylation in human breast cancer cells

  3. In an Eastern Chinese population, carriers of MAP2K7 rs3679T variant genotypes had an increased risk of NSCLC.

  4. Therefore, EGF (显示 EGF 抗体) is suggested to induce E-cadherin (显示 CDH1 抗体) down-regulation at the transcriptional level through the MEK (显示 MAP2K1 抗体)/ERK (显示 EPHB2 抗体) pathway, which might result in, at least in part, the induction of cellular morphological changes and cell migration in LoVo cells.

  5. combined pan-RAF and MEK inhibition can overcome intrinsic and acquired resistance to single-agent RAF/MEK inhibition, supporting dual pan-RAF and MEK inhibition as a novel therapeutic strategy for BRAF- and KRAS-mutant cancers

  6. our study suggested that black rice anthocyanins extract suppress metastasis in breast cancer cells by targeting the RAS/RAF (显示 RAF1 抗体)/MAPK (显示 MAPK1 抗体) pathway

  7. Crystal structures of the wild type and C218S mutant of MAP2K7 were determined. Cys218 plays a crucial role in configuring an auto-inhibition form of MAP2K7.

  8. We found that the MKK7 p.Glu116Lys rare polymorphism was significantly associated with lung cancer risk, progression and prognosis

  9. we explored the effects of selumetinib in combination with gefitinib in a panel of TNBC cells, in order to evaluate whether the simultaneous blockade of the EGFR (显示 EGFR 抗体) and the RAS/MEK (显示 MAP2K1 抗体)/ERK (显示 EPHB2 抗体) pathway might increase the antitumor activity of selumetinib in TNBC.

  10. a widespread role for the JNK (显示 MAPK8 抗体)-CELF2 (显示 CELF2 抗体) axis in controlling splicing during T-cell activation, including a specific role in propagating JNK (显示 MAPK8 抗体) signaling.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) interaction partners

  1. The loss of mkk4 (显示 MAP2K4 抗体) and mkk7 locks damaged exocrine cells in a permanently de-differentiated state.

  2. Arrestin-3 (显示 ARRB2 抗体) directly interacts with MKK7 and promotes JNK3alpha2 phosphorylation by both MKK4 (显示 MAP2K4 抗体) and MKK7 in vitro as well as in intact cells.

  3. MKK7 is specifically phosphorylated in the neurite shaft which triggers Map1b (显示 MAP1B 抗体) phosphorylation to regulate microtubule bundling leading to neurite elongation.

  4. Data indicate that mitogen activated protein kinase kinase 7 (MKK7) plays a critical regulatory role in the c-Jun N-terminal kinase pathway in a murine model of rheumatoid arthritis.

  5. a novel function for the stress kinase MKK7 as a regulator of the circadian clock in mammalian cells at steady state.

  6. Distinct signaling properties of mitogen-activated protein kinase kinases 4 (MKK4) and 7 (MKK7) in embryonic stem cell (ESC) differentiation.

  7. MKK4 (显示 MAP2K4 抗体)/7 and JNK1 (显示 MAPK8 抗体)/2 played regulatory role in cytoskeleton reorganization during vaccinia virus infection.

  8. This study demonistrated that Stress-activated protein kinase (显示 CDK7 抗体) MKK7 regulates axon elongation in the developing cerebral cortex.

  9. The results reveal an essential role of MKK7 in cardiomyocytes for protecting the heart from hypertrophic insults thereby preventing the transition to heart failure.

  10. The role of NF-kappaB (显示 NFKB1 抗体) and c-jun N-terminal kinase (JNK) activation in RANKL (显示 TNFSF11 抗体)-induced osteoclast differentiation was investigated using an adenovirus vector carrying the dominant negative 1kappaB kinase 2 gene or dominant negative MKK7 gene.

MAP2K7 抗原简介

Antigen Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined.

Alternative names and synonyms associated with MAP2K7

  • mitogen-activated protein kinase kinase 7 (MAP2K7) 抗体
  • mitogen activated protein kinase kinase 7 (Map2k7) 抗体
  • mitogen-activated protein kinase kinase 7 (Map2k7) 抗体
  • mitogen-activated protein kinase kinase 7 (map2k7) 抗体
  • 2 抗体
  • 5930412N11Rik 抗体
  • JNKK 抗体
  • JNKK 2 抗体
  • Jnkk2 抗体
  • MAP2K7 抗体
  • map2k7-A 抗体
  • MAPKK7 抗体
  • MAPKK 7 抗体
  • Mek7 抗体
  • MEK 7 抗体
  • MKK7 抗体
  • Prkmk7 抗体
  • SAPKK-4 抗体
  • SAPKK4 抗体
  • sek2 抗体
  • si:ch211-254d18.2 抗体

Protein level used designations for MAP2K7

mitogen-activated protein kinase kinase 7 , JNK kinase 2 , JNK-activating kinase 2 , JNKK 2 , MAP kinase kinase 7 , MAPK/ERK kinase 7 , MAPKK 7 , MEK 7 , c-Jun N-terminal kinase kinase 2 , dual specificity mitogen-activated protein kinase kinase 7 , SAPK kinase 4 , stress-activated protein kinase kinase 4 , mitogen activated protein kinase kinase 7 , protein kinase, mitogen activated, kinase 7

GENE ID SPECIES
787278 Bos taurus
100302082 Ovis aries
363855 Rattus norvegicus
5609 Homo sapiens
485004 Canis lupus familiaris
26400 Mus musculus
560913 Danio rerio
394391 Xenopus laevis
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