anti-MAP2K3 (MAP2K3) 抗体产品概述

Full name:
anti-Mitogen-Activated Protein Kinase Kinase 3 抗体 (MAP2K3)
在www.antibodies-online.cn可供311 Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) 抗体的29不同的供货商。 再加上,我们可以发MAP2K3 蛋白 (15)MAP2K3 试剂盒 (12)和数多这个蛋白质的别的产品。 总共356 MAP2K3产品已列进来了。
别名:
AW212142, map2k3, MAPKK3, MEK3, MKK3, mMKK3b, Prkmk3, SAPKK-2, SAPKK2, zMKK3
列出全部抗体 基因 基因ID UniProt
MAP2K3 303200  
MAP2K3 5606 P46734
MAP2K3 26397 O09110

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引用最多的anti-MAP2K3 抗体

  1. Human Polyclonal MAP2K3 Primary Antibody for IF, IHC (p) - ABIN197296 : Wang, Chen, Liao, Deng, Zhou, Huang, Sun: Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence. in Molecular and cellular biology 2002 (PubMed)
    Show all 2 references for 197296

  2. Human Polyclonal MAP2K3 Primary Antibody for IF, IHC (p) - ABIN196862 : Raingeaud, Whitmarsh, Barrett, Dérijard, Davis: MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. in Molecular and cellular biology 1996 (PubMed)
    Show all 2 references for 196862

  3. Cow (Bovine) Polyclonal MAP2K3 Primary Antibody for IHC, WB - ABIN2777128 : Prickett, Brautigan: Cytokine activation of p38 mitogen-activated protein kinase and apoptosis is opposed by alpha-4 targeting of protein phosphatase 2A for site-specific dephosphorylation of MEK3. in Molecular and cellular biology 2007 (PubMed)

  4. Human Polyclonal MAP2K3 Primary Antibody for ELISA, WB - ABIN1533090 : Dérijard, Raingeaud, Barrett, Wu, Han, Ulevitch, Davis: Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms. in Science (New York, N.Y.) 1995 (PubMed)

更多抗MAP2K3的相互作用对抗体

Human Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) interaction partners

  1. The results revealed upregulation of MEK3, as well as phosphorylated MEK3 and phosphorylated p38 MAPK (显示 MAPK14 抗体), in CMM patients. These results provide a "fingerprint" for mechanistic studies of CMM in the future and highlight the importance of MEK3-p38 MAPK (显示 MAPK14 抗体) activation in CMM.

  2. miR (显示 MLXIP 抗体)-21 targets MKK3 in vivo and in vitro, inhibiting the downstream factors IL-6 (显示 IL6 抗体) and TNF-alpha (显示 TNF 抗体), in ischemia pretreatment protection from ischemia-reperfusion induced kidney injury.

  3. MKK3 overexpression upregulated the cyclin-dependent kinase (显示 CDK1 抗体) inhibitors, p16 INK4A (显示 CDKN2A 抗体) and p15 INK4B (显示 CDKN2B 抗体) in hepatocellular carcinoma cells was Bim1, was downregulated following MKK3 overexpression.

  4. Our results suggest that asthma is associated with MKK3 over-expression in CD8 (显示 CD8A 抗体)+ cells; we have also demonstrated that MKK3 may be critical for airway neutrophilia

  5. MicroRNA-21 promotes hepatocellular carcinoma HepG2 cell proliferation through repression of mitogen-activated protein kinase-kinase 3.

  6. study detected higher MKK3 activation in isolated peripheral blood mononuclear cells from septic patients compared with nonseptic controls

  7. study concludes MAP2K3 is a reproducible obesity locus that may affect body weight via complex mechanisms involving appetite regulation and hypothalamic inflammation

  8. miR-20a acts in a feedback loop to repress the expression of MKK3 and to negatively regulate the p38 pathway-mediated VEGF-induced endothelial cell migration and angiogenesis

  9. Data suggest aberrant MAP2K protein (MKK3, MKK4 (显示 MAP2K4 抗体), MKK6 (显示 MAP2K6 抗体), and MKK7 (显示 MAP2K7 抗体)) expression indicates that altered cellular signal transduction mediated via JNK (显示 MAPK8 抗体) and p38 (显示 CRK 抗体) may be common in bladder cancer.

  10. the balance between MKK6 (显示 MAP2K6 抗体) and MKK3 mediates p38 MAPK (显示 MAPK14 抗体) associated resistance to cisplatin in NSCLC

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) interaction partners

  1. ATF3 (显示 ATF3 抗体) upregulation in cardiac fibroblasts in response to hypertensive stimuli protects the heart by suppressing Map2K3 expression and subsequent p38 (显示 CRK 抗体)-transforming growth factor-beta signaling.

  2. miR (显示 MLXIP 抗体)-21 targets MKK3 in vivo and in vitro, inhibiting the downstream factors IL-6 (显示 IL6 抗体) and TNF-alpha (显示 TNF 抗体), in ischemia pretreatment protection from ischemia-reperfusion induced kidney injury.

  3. miR (显示 MLXIP 抗体)-21a-5p inhibited BPA (显示 DST 抗体) induced adipocyte differentiation by targeting map2k3 through MKK3/p38/MAPK (显示 MAPK14 抗体) in 3T3-L1 cells

  4. this study demonstrates that MKK3 influences mitochondrial quality by affecting the expression of mitochondrial proteins, including TCA cycle enzymes, and mitophagy, which consequently regulates the inflammatory response.

  5. Exendin-4 treatment improves cardiac function, attenuates cardiac remodeling, and promotes angiogenesis in the infarcted myocardium through MKK3 and Akt-1 (显示 AKT1 抗体) pathway.

  6. Our results suggest that asthma is associated with MKK3 over-expression in CD8 (显示 CD8A 抗体)+ cells; we have also demonstrated that MKK3 may be critical for airway neutrophilia

  7. MKK3 and MKK6 (显示 MAP2K6 抗体) differentially regulate bone loss due to estrogen withdrawal. MKK3 directly mediates osteoclastogenesis while MKK6 (显示 MAP2K6 抗体) likely contributes to pro-inflammatory cytokine production that promotes osteoclast formation.

  8. results designate MKK3 as a novel, positive regulator of SCF (显示 KITLG 抗体)-induced mast cell proliferation and a critical signaling protein for AP-1 (显示 JUN 抗体)-dependent IL-6 (显示 IL6 抗体) production

  9. findings demonstrate a critical role for mitochondria in the pathogenesis of sepsis that involves a previously unrecognized function of MKK3 in mitochondrial quality control

  10. Endothelial MKK3 is neede for inflammatory cell recruitment to the lungs, mitochondrial oxidant-mediated AP-1 (显示 JUN 抗体), NF-kappaB (显示 NFKB1 抗体) activation, & ICAM-1 (显示 ICAM1 抗体) expression during LPS (显示 TLR4 抗体) challenge.

MAP2K3 抗原简介

Antigen Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene.

Alternative names and synonyms associated with MAP2K3

  • MAP kinase activator XMEK3 (map2k3) 抗体
  • mitogen activated protein kinase kinase 3 (Map2k3) 抗体
  • mitogen-activated protein kinase kinase 3 (MAP2K3) 抗体
  • mitogen-activated protein kinase kinase 3 (Map2k3) 抗体
  • mitogen-activated protein kinase kinase 6 (map2k6) 抗体
  • AW212142 抗体
  • map2k3 抗体
  • MAPKK3 抗体
  • MEK3 抗体
  • MKK3 抗体
  • mMKK3b 抗体
  • Prkmk3 抗体
  • SAPKK-2 抗体
  • SAPKK2 抗体
  • zMKK3 抗体

Protein level used designations for MAP2K3

MAP kinase kinase 3 , MAPK/ERK kinase 3 , MAPKK 3 , MEK 3 , SAPK kinase 2 , dual specificity mitogen-activated protein kinase kinase 3 , stress-activated protein kinase kinase 2 , mitogen activated protein kinase kinase 3 , protein kinase, mitogen-activated, kinase 3 , MAP kinase kinase 6 , MAPKK 6 , dual specificity mitogen-activated protein kinase kinase 6 , mitogen-activated protein kinase kinase 3

GENE ID SPECIES
399150 Xenopus laevis
303200 Rattus norvegicus
5606 Homo sapiens
489547 Canis lupus familiaris
26397 Mus musculus
516039 Bos taurus
416496 Gallus gallus
65239 Danio rerio
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