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DIABLO 抗体

DIABLO 适用: 人 WB, EIA 宿主: 小鼠 Monoclonal 2D12 unconjugated
产品编号 ABIN371649
发货至: 中国
  • 抗原 See all DIABLO 抗体
    DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
    适用
    • 61
    • 28
    • 27
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    宿主
    • 55
    • 6
    • 1
    小鼠
    克隆类型
    • 45
    • 17
    单克隆
    标记
    • 37
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    • 3
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    • 3
    • 3
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    This DIABLO antibody is un-conjugated
    应用范围
    • 35
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    • 12
    • 6
    • 3
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    • 1
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    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody is specific for Human SMAC/DIABLO.
    产品特性
    Synonyms: Diablo homolog mitochondrial, Second mitochondria-derived activator of caspase, DirectIAP-binding protein with low pI
    纯化方法
    Purified
    克隆位点
    2D12
    亚型
    IgG2b
    Top Product
    Discover our top product DIABLO Primary Antibody
  • 应用备注
    ELISA: 1/1,000-1/2,000. Western Blot: 1/5,000-1/10,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    100 mM Borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
    别名
    DIABLO / SMAC (DIABLO 产品)
    别名
    smac antibody, smac3 antibody, diablo-s antibody, 0610041G12Rik antibody, 1700006L01Rik antibody, AU040403 antibody, Smac antibody, DFNA64 antibody, SMAC antibody, DBO antibody, XSmac antibody, diablo, IAP-binding mitochondrial protein antibody, diablo IAP-binding mitochondrial protein antibody, diablo, IAP-binding mitochondrial protein L homeolog antibody, diablo antibody, Diablo antibody, DIABLO antibody, diablo.L antibody
    背景
    SMAC/DIABLO (second mitochondria-derived activator of caspase/direct IAP-binding protein with low PI) is a mitochondrial protein that functions as a regulatory component during apoptosis. It is encoded by a nuclear gene and is subsequently imported into the mitochondria where the N-terminus is removed generating the mature form of the molecule. SMAC/DIABLO has been shown to neutralize the antiapoptotic effect of the inhibitor of apoptosis protein (IAP) family, a major group of apoptosis regulators that have been shown to directly block caspase activity thereby blocking apoptosis. (Ref.1-6)Synonyms: Diablo homolog mitochondrial, Direct IAP-binding protein with low pI, Second mitochondria-derived activator of caspase
    基因ID
    56616
    UniProt
    Q9NR28
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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