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DIABLO 抗体 (AA 56-239)

Name: DIABLO 抗体 (AA 56-239)
SKU: ABIN3044515
Availability: OutOfStock

This 兔多克隆 antibody specifically detects DIABLO in WB, IHC, ELISA, IF, FACS, IP 和 ICC. It exhibits reactivity toward 人, 小鼠和大鼠.It has been mentioned in 1 publication

Western blot analysis of Smac/Diablo expression in rat testis extract (lane 1), 22RV1 whole cell lysates (lane 2) and SKOV whole cell lysates (lane 3). (DIABLO 抗体 (AA 56-239))

Smac/Diablo was detected in paraffin-embedded sections of rat testis tissues using rabbit anti- Smac/Diablo Antigen Affinity purified polyclonal antibody at 1 μg/mL. (DIABLO 抗体 (AA 56-239))

IHC (p)

Smac/Diablo was detected in paraffin-embedded sections of mouse testis tissues using rabbit anti- Smac/Diablo Antigen Affinity purified polyclonal antibody at 1 μg/mL. (DIABLO 抗体 (AA 56-239))

IHC (p)

Smac/Diablo was detected in paraffin-embedded sections of human testis tissues using rabbit anti- Smac/Diablo Antigen Affinity purified polyclonal antibody at 1 μg/mL. (DIABLO 抗体 (AA 56-239))

IHC (p)

4 images

(1 reference)

产品编号 ABIN3044515

发货至: 中国

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Quick Overview for DIABLO 抗体 (AA 56-239) (ABIN3044515)

抗原

See all DIABLO 抗体

DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This DIABLO antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Discover our top product DIABLO Primary Antibody

抗原表位
14

12

5

3

3

3

2

2

1

1

1

1

1
AA 56-239

原理

Anti-Smac/Diablo Antibody

特异性

No cross reactivity with other proteins.

交叉反应（详细）

No cross-reactivity with other proteins.

预测反应

coli-derived human Smac,Diablo recombinant protein (Position: A56-D239). Human Smac,Diablo shares 88.6% amino acid (aa) sequence identity with mouse Smac,Diablo.

产品特性

Anti-Smac/Diablo Antibody. Tested in ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

纯化方法

Immunogen affinity purified.

免疫原

E. coli-derived human Smac/Diablo recombinant protein (Position: A56-D239). Human Smac/Diablo shares 88.6% amino acid (aa) sequence identity with mouse Smac/Diablo.

亚型

IgG
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 211-239), (C-Term) antibody
DIABLO 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20755 unconjugated

anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 1-232) antibody
DIABLO 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated

anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 131-239) antibody
DIABLO 适用: 人 WB, IHC (p), IF (cc) 宿主: 兔 Polyclonal unconjugated

anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) antibody
DIABLO 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 79-1-83 unconjugated

anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) antibody
KD Validated DIABLO 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2575 unconjugated Recombinant Antibody

anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) antibody
KO Validated DIABLO 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2055 unconjugated Recombinant Antibody

anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 1-239) antibody
DIABLO 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 225-239) antibody
DIABLO 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 168-236) antibody
DIABLO 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 56-239) antibody
DIABLO 适用: 人 WB, ELISA, IF, FACS, ICC 宿主: 小鼠 Monoclonal AT19F2 unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Immunoprecipitation, 0.5-2 μg/mL, Human Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
You, Li, Jin, Zheng, Chen, Yang: "Genistein protects against Aβ25-35 induced apoptosis of PC12 cells through JNK signaling and modulation of Bcl-2 family messengers." in: BMC neuroscience, Vol. 18, Issue 1, pp. 12, (2017) (PubMed).
抗原

DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

别名

DIABLO

背景

Background: Diablo homolog (DIABLO), also referred to as second mitochondria-derived activator of caspases or SMAC, is a mitochondrial protein that in humans is encoded by the DIABLO ( IAP binding protein with low pI) gene on chromosome 12. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Full Name: diablo IAP-binding mitochondrial protein

分子量

20 kDa

基因ID

56616

UniProt

Q9NR28

途径

Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity