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DIABLO 抗体 (C-Term)

DIABLO 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20755 unconjugated
产品编号 ABIN6243156
发货至: 中国
  • 抗原 See all DIABLO 抗体
    DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
    抗原表位
    • 9
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 211-239, C-Term
    适用
    • 61
    • 28
    • 27
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 54
    • 7
    • 1
    克隆类型
    • 44
    • 18
    多克隆
    标记
    • 37
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    This DIABLO antibody is un-conjugated
    应用范围
    • 35
    • 17
    • 14
    • 11
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This SMAC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-239 amino acids from the C-terminal region of human SMAC.
    克隆位点
    RB20755
    亚型
    Ig Fraction
  • 应用备注
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Abulwerdi, Liao, Liu, Azmi, Aboukameel, Mady, Gulappa, Cierpicki, Owens, Zhang, Sun, Stuckey, Mohammad, Nikolovska-Coleska: "A novel small-molecule inhibitor of mcl-1 blocks pancreatic cancer growth in vitro and in vivo." in: Molecular cancer therapeutics, Vol. 13, Issue 3, pp. 565-75, (2014) (PubMed).

  • 抗原
    DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
    别名
    SMAC (DIABLO 产品)
    别名
    smac antibody, smac3 antibody, diablo-s antibody, 0610041G12Rik antibody, 1700006L01Rik antibody, AU040403 antibody, Smac antibody, DFNA64 antibody, SMAC antibody, DBO antibody, XSmac antibody, diablo, IAP-binding mitochondrial protein antibody, diablo IAP-binding mitochondrial protein antibody, diablo, IAP-binding mitochondrial protein L homeolog antibody, diablo antibody, Diablo antibody, DIABLO antibody, diablo.L antibody
    背景
    SMAC is an inhibitor of apoptosis protein (IAP)-binding protein. This mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs.
    分子量
    27131
    NCBI登录号
    NP_001265231, NP_001265232, NP_001265233, NP_001265271, NP_063940, NP_620308
    UniProt
    Q9NR28
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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