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GRB2 抗体 (N-Term)
GRB2
适用: 人, 小鼠, 大鼠
WB
宿主: 小鼠
Monoclonal
3F2
unconjugated
GRB2抗体详情
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抗原
See all GRB2 抗体
GRB2
(Growth Factor Receptor-Bound Protein 2 (GRB2))
抗原表位
All epitopes for GRB2 抗体
N-Term
适用
All reactivities for GRB2 抗体
人, 小鼠, 大鼠
宿主
All hosts for GRB2 抗体
小鼠
克隆类型
All clonalities for GRB2 抗体
单克隆
标记
All conjugates for GRB2 抗体
This GRB2 antibody is un-conjugated
应用范围
All applications for GRB2 抗体
Western Blotting (WB)
交叉反应 (详细)
Species reactivity (tested):Human, Mouse, Rat
纯化方法
Ammonium sulfate precipitation and affinity chromatography on protein A
免疫原
Recombinant Ash/Grb-2
克隆位点
3F2
亚型
IgG1
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Discover our top product GRB2 Primary Antibody
Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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溶解方式
Restore with 100 μL of distilled water.
缓冲液
PBS, 1 mg/mL Sodium azide, 10 mg/mL sucrose
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted (in aliquots) at -20 °C.
GRB2目标详情
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抗原
GRB2
(Growth Factor Receptor-Bound Protein 2 (GRB2))
别名
GRB2 / ASH (GRB2 产品 )
别名
GRB2 antibody, grb2 antibody, AA408164 antibody, Ash antibody, ASH antibody, EGFRBP-GRB2 antibody, Grb3-3 antibody, MST084 antibody, MSTP084 antibody, NCKAP2 antibody, wu:fb18e12 antibody, wu:fb34e06 antibody, zgc:73077 antibody, growth factor receptor bound protein 2 antibody, growth factor receptor-bound protein 2 antibody, growth factor receptor-bound protein 2b antibody, GRB2 antibody, grb2 antibody, Grb2 antibody, grb2b antibody
背景
Grb2 (Growth factor receptor bound protein 2) also known as Ash, is a 25-28 kDa molecule composed of central Src homology (SH2) domain and SH3 domains. Grb2 associates with tyrosine phosphorylated proteins such as EGFR, PDGFR, IRS-1, Shc and Gab1 via its Sh2 domain. The SH3 domain of Grb2 binds to Sos, which stimulates the GTP binding activity of Ras, cause activation of MAP kinase and other signaling pathways. Grb2 is an adaptor protein, which does not have enzymatic activity itself. Grb2 express ubiquitously and has two isoforms.Synonyms: Growth factor receptor-bound protein 2
基因ID
2885
NCBI登录号
NP_002077
UniProt
P62993
途径
RTK signaling , TCR Signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Regulation of Actin Filament Polymerization , Hepatitis C , Signaling Events mediated by VEGFR1 and VEGFR2 , Signaling of Hepatocyte Growth Factor Receptor , EGFR Downregulation
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