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GRB2 抗体 (N-Term)

GRB2 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 3F2 unconjugated
产品编号 ABIN1449302
发货至: 中国
  • 抗原 See all GRB2 抗体
    GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
    抗原表位
    • 8
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 62
    • 29
    • 28
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 51
    • 8
    • 3
    小鼠
    克隆类型
    • 52
    • 9
    • 1
    单克隆
    标记
    • 43
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GRB2 antibody is un-conjugated
    应用范围
    • 47
    • 33
    • 18
    • 12
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse, Rat
    纯化方法
    Ammonium sulfate precipitation and affinity chromatography on protein A
    免疫原
    Recombinant Ash/Grb-2
    克隆位点
    3F2
    亚型
    IgG1
    Top Product
    Discover our top product GRB2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    Restore with 100 μL of distilled water.
    缓冲液
    PBS, 1 mg/mL Sodium azide, 10 mg/mL sucrose
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted (in aliquots) at -20 °C.
  • 抗原
    GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
    别名
    GRB2 / ASH (GRB2 产品)
    别名
    GRB2 antibody, grb2 antibody, AA408164 antibody, Ash antibody, ASH antibody, EGFRBP-GRB2 antibody, Grb3-3 antibody, MST084 antibody, MSTP084 antibody, NCKAP2 antibody, wu:fb18e12 antibody, wu:fb34e06 antibody, zgc:73077 antibody, growth factor receptor bound protein 2 antibody, growth factor receptor-bound protein 2 antibody, growth factor receptor-bound protein 2b antibody, GRB2 antibody, grb2 antibody, Grb2 antibody, grb2b antibody
    背景
    Grb2 (Growth factor receptor bound protein 2) also known as Ash, is a 25-28 kDa molecule composed of central Src homology (SH2) domain and SH3 domains. Grb2 associates with tyrosine phosphorylated proteins such as EGFR, PDGFR, IRS-1, Shc and Gab1 via its Sh2 domain. The SH3 domain of Grb2 binds to Sos, which stimulates the GTP binding activity of Ras, cause activation of MAP kinase and other signaling pathways. Grb2 is an adaptor protein, which does not have enzymatic activity itself. Grb2 express ubiquitously and has two isoforms.Synonyms: Growth factor receptor-bound protein 2
    基因ID
    2885
    NCBI登录号
    NP_002077
    UniProt
    P62993
    途径
    RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, EGFR Downregulation
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