Nicotinamide phosphoribosyltransferase 蛋白 (NAMPT)

NAMPT encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. 再加上,我们可以发NAMPT 抗体 (353)NAMPT 试剂盒 (112)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
NAMPT 10135 P43490
NAMPT 59027 Q99KQ4
NAMPT 297508 Q80Z29

antibodies-online.cn销售最多的NAMPT 蛋白

Showing 10 out of 59 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
大肠杆菌(E. Coli) His tag Dimer formation of recombinant Nampt (Visfatin, PBEF) . Purified Nampt (Visfatin, PBEF) was separated by SDS-PAGE and Western blot analysis was performed using rabbit anti-Nampt polyclonal antibody . In the absence of DTT, Nampt (visfatin, PBEF) formed a homodimer, a homomultimer. 50 μg Log in to see 23至30个工作日
¥11,346.87
详细
大肠杆菌(E. Coli) 小鼠 非结合性 50 μg Log in to see 24至29个工作日
¥4,308.06
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大肠杆菌(E. Coli) 小鼠 His tag   50 μg Log in to see 23至30个工作日
¥11,346.87
详细
HOST_HEK-293 Cells 大鼠 DYKDDDDK Tag   10 μg Log in to see 23至30个工作日
¥5,937.32
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 78至82个工作日
¥195,007.14
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Insect Cells 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 78至82个工作日
¥195,007.14
详细
大肠杆菌(E. Coli) His tag 100 μg Log in to see 33至41个工作日
¥3,331.12
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大肠杆菌(E. Coli) 小鼠 His tag 100 μg Log in to see 33至41个工作日
¥4,185.30
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大肠杆菌(E. Coli) 非结合性   50 μg Log in to see 24至29个工作日
¥4,308.06
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大肠杆菌(E. Coli) 非结合性   5 μg Log in to see 28至34个工作日
¥710.27
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NAMPT 蛋白 by Origin and Source

Origin 在表达 标记
Human , , , ,
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Mouse (Murine) , ,
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Rat (Rattus) , ,
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引用最多的NAMPT 蛋白

  1. Human NAMPT Protein expressed in Escherichia coli (E. coli) - ABIN2667609 : Sommer, Garten, Petzold, Beck-Sickinger, Blüher, Stumvoll, Fasshauer: Visfatin/PBEF/Nampt: structure, regulation and potential function of a novel adipokine. in Clinical science (London, England : 1979) 2008 (PubMed)
    Show all 4 references for 2667609

  2. Human NAMPT Protein expressed in Escherichia coli (E. coli) - ABIN413884 : Šenolt, Kuklová, Cerezo, Hulejová, Filková, Bošanská, Pecha, Pavelka, Haluzík, Vencovský: Adipokine profile is modulated in subcutaneous adipose tissue by TNFα inhibitors in patients with rheumatoid arthritis. in Annals of the rheumatic diseases 2011 (PubMed)
    Show all 2 references for 413884

  3. Mouse (Murine) NAMPT Protein expressed in Escherichia coli (E. coli) - ABIN667699 : Hug, Lodish: Medicine. Visfatin: a new adipokine. in Science (New York, N.Y.) 2005 (PubMed)
    Show all 2 references for 667699

  4. Human NAMPT Protein expressed in Escherichia coli (E. coli) - ABIN1344091 : Yonezawa, Haga, Kobayashi, Takahashi, Obara: Visfatin is present in bovine mammary epithelial cells, lactating mammary gland and milk, and its expression is regulated by cAMP pathway. in FEBS letters 2006 (PubMed)
    Show all 2 references for 1344091

  5. Human NAMPT Protein expressed in Escherichia coli (E. coli) - ABIN666706 : Stephens, Vidal-Puig: An update on visfatin/pre-B cell colony-enhancing factor, an ubiquitously expressed, illusive cytokine that is regulated in obesity. in Current opinion in lipidology 2006 (PubMed)

  6. Rat (Rattus) NAMPT Protein expressed in HEK-293 Cells - ABIN1344283 : Spinnler, Gorski, Stolz, Schuster, Garten, Beck-Sickinger, Engelse, de Koning, Körner, Kiess, Maedler: The adipocytokine Nampt and its product NMN have no effect on beta-cell survival but potentiate glucose stimulated insulin secretion. in PLoS ONE 2013 (PubMed)

  7. Mouse (Murine) NAMPT Protein expressed in Escherichia coli (E. coli) - ABIN413887 : Kanda, Hau, Tada, Tatsuta, Sato, Watanabe: Visfatin enhances CXCL8, CXCL10, and CCL20 production in human keratinocytes. in Endocrinology 2011 (PubMed)

  8. Mouse (Murine) NAMPT Protein expressed in Escherichia coli (E. coli) - ABIN1344090 : Brown, Onyango, Ramanjaneya, Conner, Patel, Dunmore, Randeva: Visfatin regulates insulin secretion, insulin receptor signalling and mRNA expression of diabetes-related genes in mouse pancreatic beta-cells. in Journal of molecular endocrinology 2010 (PubMed)

更多Nicotinamide phosphoribosyltransferase (NAMPT)互动伙伴

Human Nicotinamide phosphoribosyltransferase (NAMPT) interaction partners

  1. Visfatin increases the nuclear translocation of Akt (显示 AKT1 蛋白) and its binding with ABCC1 (显示 ABCC1 蛋白). These data showed that visfatin can decrease doxorubicin sensitivity of Non-small-cell lung cancer cells via activation of Akt (显示 AKT1 蛋白)/MRP1 (显示 MDM4 蛋白).

  2. Results suggest a mechanism by which tumor cells protect themselves against glucose deprivation-induced oxidative stress by utilizing nicotinamide phosphoribosyltransferase (NAMPT) to maintain NADPH (显示 NQO1 蛋白) levels.

  3. The combination of upregulation of the NAD(+) de novo synthesis pathway through QPRT (显示 QPRT 蛋白) over-expression and NAMPT mutation confers resistance to GMX1778, but the cells are only partially resistant to next-generation NAMPT inhibitors. The resistance mechanisms uncovered herein provide a potential avenue to continue exploration of next generation NAMPT inhibitors to treat neoplasms in the clinic.

  4. this study shows that upstream visfatin SNPs could potentially affect phenotypic outcome in obese children through alteration of circulating visfatin level.

  5. Lack of changes in serum visfatin level despite the changes in visfatin mRNA expression of adipose tissue suggests paracrine effect of visfatin rather than endocrine

  6. Ascending aorta from aortic aneurysm patient,s revealed an inverse relationship between smooth muscle cell NAMPT content and aortic diameter.

  7. Visfatin significantly correlated with BMI and hot flashes number in postmenopausal women with metabolic syndrome.

  8. Single nucleotide polymorphism in the NAMPT gene is associated with inflammation in chronic kidney disease.

  9. our present study revealed that visfatin is over-expressed in colorectal cancer doxorubicin-resistant cells; visfatin mediates doxorubicin resistance via upregulation of MDR1

  10. Nampt inhibition may override gemcitabine resistance by decreasing the NAD level and suppressing glycolytic activity in pancreatic neoplasms.

Mouse (Murine) Nicotinamide phosphoribosyltransferase (NAMPT) interaction partners

  1. role of Nampt in regulating osteoblast differentiation in primary mouse bone marrow-derived mesenchymal stem cells (BM-MSCs); Nampt expression was progressively elevated during BM-MSCs osteogenic differentiation

  2. The results suggest that NCOA6 (显示 NCOA6 蛋白) stimulates insulin (显示 INS 蛋白) secretion, at least partially, by modulating Nampt expression in pancreatic beta-cells.

  3. the protein expression levels of TIMP-2 (显示 TIMP2 蛋白) and PBEF in cloned placentae, were examined.

  4. NAMPT inhibited endothelial progenitor cell senescence through an SIRT1 (显示 SIRT1 蛋白) AS lncRNA/miR (显示 MLXIP 蛋白)-22/SIRT1 (显示 SIRT1 蛋白) pathway

  5. Visfatin upregulated CD36 (显示 CD36 蛋白) and SRA (显示 MSR1 蛋白) expression and downregulated ABCA1 (显示 ABCA1 蛋白) and ABCG1 (显示 ABCG1 蛋白) expression, subsequently increased ox-LDL uptake and decreased cholesterol efflux, and finally promoted foam cell formation via the PI3K- and ERK (显示 EPHB2 蛋白)-dependent pathways.

  6. results support a novel, important role for Nampt-mediated NAD(+) biosynthesis in long-term depression and in the function of GluN2B (显示 GRIN2B 蛋白)-containing NMDARs

  7. extracellular NAMPT can be actively released by melanoma cells in vitro.

  8. We now report that NAMPT/PBEF induces lung NFkappaB transcriptional activities and inflammatory injury via direct ligation of Toll-like receptor 4 (TLR4 (显示 TLR4 蛋白)).

  9. Visfatin plays an important role in glucose metabolism via the calcium mediated AMPK (显示 PRKAA1 蛋白)-p38 MAPK (显示 MAPK14 蛋白) pathway.

  10. Deacetylation of intracellular NAMPT by the mammalian NAD(+)-dependent deacetylase SIRT1 (显示 SIRT1 蛋白) predisposes the protein to secretion in adipocytes.

Pig (Porcine) Nicotinamide phosphoribosyltransferase (NAMPT) interaction partners

  1. In a wild boar x Meishan F2 family nicotinamide phosphoribosyltransferase nicotinamide phosphoribosyltransferase SNP 669T>C was associated with muscling, fat deposition, growth and fattening, meat quality and other traits.

  2. cloning and characterization of porcine visfatin and its three alternate splicing variants is reported; sequence analysis indicated that variant 1 is the predominant form among species.

  3. The porcine visfatin gene cannot be considered as a marker of fat accumulation since the highest visfatin expression levels were associated with the leaner (显示 CACNA1A 蛋白) animals.

Cow (Bovine) Nicotinamide phosphoribosyltransferase (NAMPT) interaction partners

  1. Exposure to follicular fluid transiently increased the transcript levels of IL8 (显示 IL8 蛋白) and PTGS2 (显示 PTGS2 蛋白), and decreased the expression of SOD2 (显示 SOD2 蛋白), GPX3 (显示 GPX3 蛋白), DAB2 (显示 DAB2 蛋白), and NR3C1 (显示 NR3C1 蛋白). TNF (显示 TNF 蛋白) and IL6 (显示 IL6 蛋白) levels were also decreased while those of NAMPT were unaffected.

  2. the presence of 35bp-insertion in visfatin gene may influence the birth weight and bodyweight in 6-month-old cows.

  3. These results indicate that mammary epithelial cells express the visfatin protein and secrete them into the milk.

蛋白简介NAMPT

蛋白简介

This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10.

Gene names and symbols associated with NAMPT

  • nicotinamide phosphoribosyltransferase (NAMPT)
  • nicotinamide phosphoribosyltransferase (nampt)
  • Nicotinamide phosphoribosyltransferase (Smon_0680)
  • Nicotinamide phosphoribosyltransferase (Mrub_2845)
  • nicotinamide phosphoribosyltransferase (Cseg_3704)
  • Nicotinamide phosphoribosyltransferase (BC1002_3997)
  • nicotinamide phosphoribosyltransferase (Ftrac_2686)
  • nicotinamide phosphoribosyltransferase (Varpa_5681)
  • nicotinamide phosphoribosyltransferase (Celal_3900)
  • Nicotinamide phosphoribosyltransferase (Deima_0880)
  • Nicotinamide phosphoribosyltransferase (BC1001_3724)
  • Nicotinamide phosphoribosyltransferase (Celly_1696)
  • Nicotinamide phosphoribosyltransferase (Clole_1542)
  • Nicotinamide phosphoribosyltransferase (Psed_2146)
  • Nicotinamide phosphoribosyltransferase (Psed_2158)
  • nicotinamide phosphoribosyltransferase (Tsp_05934)
  • nicotinamide phosphoribosyltransferase (Nampt)
  • 1110035O14Rik 蛋白
  • AI314458 蛋白
  • AI480535 蛋白
  • NAmPRTase 蛋白
  • Pbef 蛋白
  • Pbef1 蛋白
  • VF 蛋白
  • visfatin 蛋白

Protein level used designations for NAMPT

pre-B-cell colony enhancing factor 1 , visfatin , Nicotinamide phosphoribosyltransferase , nicotinamide phosphoribosyltransferase , NAmPRTase , pre-B cell-enhancing factor , pre-B-cell colony-enhancing factor 1 , pre-B-cell colony-enhancing factor 1 homolog , PBEF

GENE ID SPECIES
463648 Pan troglodytes
100223583 Taeniopygia guttata
496856 Xenopus (Silurana) tropicalis
8600403 Streptobacillus moniliformis DSM 12112
8880961 Meiothermus ruber DSM 1279
9105230 Caulobacter segnis ATCC 21756
9113310 Burkholderia sp. CCGE1002
10012838 Marivirga tractuosa DSM 4126
10132554 Variovorax paradoxus EPS
10146329 Cellulophaga algicola DSM 14237
10150218 Deinococcus maricopensis DSM 21211
10225315 Burkholderia sp. CCGE1001
10263712 Cellulophaga lytica DSM 7489
10331257 Clostridium lentocellum DSM 5427
10363982 Pseudonocardia dioxanivorans CB1190
10363994 Pseudonocardia dioxanivorans CB1190
10911088 Trichinella spiralis
10135 Homo sapiens
59027 Mus musculus
398502 Xenopus laevis
417707 Gallus gallus
483267 Canis lupus familiaris
595123 Sus scrofa
297508 Rattus norvegicus
520472 Bos taurus
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